The U.S. hemoglobinopathies market size is anticipated to reach USD 6.85 billion by 2030, growing at a CAGR of 12.5% from 2024 to 2030, according to a new report by Grand View Research, Inc. The rising prevalence of hemoglobinopathies, such as sickle cell disease and thalassemia, is a significant market driver. Advances in diagnostic techniques, such as genetic testing and prenatal screening, have improved the early detection of hemoglobinopathies. In addition, ongoing research into novel treatment options, including gene therapy and gene editing technologies like CRISPR-Cas9, holds promise for more effective therapies in the future.
The growing government initiatives to raise awareness about hemoglobinopathies and improved access to care for affected individuals play a crucial role in driving the market. Funding support for research and development efforts also accelerates innovation in this field.
Collaboration between pharmaceutical companies, research institutions, and healthcare providers fosters the development of new therapies and enhances patient care. Partnerships that leverage companies’ strengths can accelerate drug development and improve treatment outcomes.
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Sickle cell disease type dominated the type segment with 60.1% share in 2023 and is expected to grow at fastest CAGR over the forecast period. The growth is attributed to the increasing Initiatives of Biopharmaceutical Companies and Nonprofit Organizations Driving Improved Access to Sickle Cell Disease (SCD) Treatment.
The sickle cell disease diagnosis segment held the largest market in 2023. Advancements including genetic testing methods such as next-generation sequencing and molecular diagnostics are propelling the segment growth.
The sickle cell disease therapy segment held the largest market in 2023. The growing approval of innovative therapies, such as gene therapies and targeted treatments, designed to modify genetic abnormalities are propelling market growth.
In April 2022, Sangamo Therapeutics, a genomic medicines company, announced the transition of its SAR445136 sickle cell disease program from Sanofi to Sangamo. This transition marks a significant step in the development of a gene-edited therapy for sickle cell disease.
Grand View Research has segmented the U.S. hemoglobinopathies market based on type, diagnosis, therapy, and region:
U.S. Hemoglobinopathies Type Outlook (Revenue, USD Million, 2018 - 2030)
Thalassemia
Sickle Cell Disease
Other Hemoglobin (Hb) Variants
U.S. Hemoglobinopathies Diagnosis Outlook (Revenue, USD Million, 2018 - 2030)
Thalassemia
Alpha
Blood Test
Genetic Test
Prenatal Genetic Test
Pre-implantation Genetic Diagnosis
Electrophoresis
Others
Beta
Blood Test
Genetic Test
Prenatal Genetic Test
Pre-implantation Genetic Diagnosis
Electrophoresis
Others
Sickle Cell Disease
Blood Test
Genetic Test
Prenatal Genetic Test
Electrophoresis
Others
(Hb) Variants
Blood Test
Genetic Test
Prenatal Genetic Test
Electrophoresis
Others
U.S. Hemoglobinopathies Therapy Outlook (Revenue, USD Million, 2018 - 2030)
Thalassemia
Alpha
Blood Transfusion
Iron Chelation Therapy
Bone Marrow Transplant
Others
Beta
Blood Transfusion
Iron Chelation Therapy
Bone Marrow Transplant
Others
Sickle Cell Disease
Blood Transfusion
Hydroxyurea
Bone Marrow Transplant
Others
(Hb) Variants
Blood Transfusion
Hydroxyurea
Bone Marrow Transplant
Others
U.S. Hemoglobinopathies Regional Outlook (Revenue, USD Million, 2018 - 2030)
West
Midwest
Northeast
Southwest
Southeast
List of Key Players in the U.S. Hemoglobinopathies Market
Sangamo Therapeutics, Inc.
Global Blood Therapeutics, Inc.
bluebird bio, Inc.
Emmaus Life Sciences Inc.
Pfizer, Inc.
Novartis AG
Prolong Pharmaceuticals, LLC
Bioverativ Inc.
Celgene Corp.
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