U.S. Clinical Oncology Next Generation Sequencing Market To Reach $500.4 Million By 2030

U.S. Clinical Oncology Next Generation Sequencing Market Growth & Trends

The U.S. clinical oncology next-generation sequencing market size is expected to reach USD 500.4 million by 2030, expanding at a CAGR of 15.04% from 2025 to 2030, according to a new report by Grand View Research, Inc. The market is expected to increase at a significant rate during the forecast period from 2023 to 2030 owing to the increasing competition among the industry players, technological advances in the field and decreasing costs for genetic sequencing.

The increasing market competition and the launch of innovative solutions based on next generation sequencing in the oncology field are expected to fuel market growth over the forecast period. For instance, in February 2023, Exact Sciences Corp., a cancer screening and diagnostic testing company, introduced the therapy selection test -OncoExTra in the U.S. It is a next-generation sequencing-based genomic test to help in cancer care. It helps in understanding and characterizing cancer tumors. Moreover, to gain a competitive edge in the industry, companies are collaborating and focusing on advancing in the next generation sequencing. For instance, in January 2020, the two key players operating in the market, Illumina, Inc and F. Hoffmann-La Roche Ltd, signed a 15-year agreement to discover NGS's potential to transform cancer detection, diagnosis, risk prediction, treatment, and monitoring.

Moreover, various articles and studies are being published on the use of NGS in oncology and cancer treatments. For instance, in June 2023, the Lancet published an article on real-world outcomes and the usefulness of NGS testing in cancer patients. Furthermore, in June 2023, the American Society Of Clinical Oncology published a study on the clinical impact of NGS tests for managing advanced cancer in the U.S. Such studies help researchers and clinicians increase awareness and knowledge about the use of NGS for cancer treatments.

Furthermore, the growth of the clinical oncology next-generation sequencing market during the forecast period is expected to witness growth due to reduced sequencing costs. The costs of NGS can be reduced by increasing parallel sequencing and running multiple flow cells to increase sequencing capacity without raising the costs associated with it. These factors are anticipated to boost the market demand over the forecast period in the U.S.

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U.S. Clinical Oncology Next Generation Sequencing Market Report Highlights

• NGS sequencing accounted for the largest revenue share of 56.65% in 2024 based on the workflow segment. The dominance of the segments is due to the increasing number of cancer sequencing projects and technological advances in the field.

• Based on the technology, targeted sequencing & resequencing dominated the market with a revenue share of 72.51% in 2024. This can be attributed to the rising use of targeted panels and their efficiency in identifying cancer tumors.

• Based on the application, the screening segment dominated the U.S. clinical oncology NGS market with a revenue share of 79.94% in 2024, owing to the growing prevalence of cancer disorder across the country.

• Based on the end-use, the laboratories segment accounted for the largest share of 63.47% in the U.S. clinical oncology NGS market in 2024. This dominance of the segment is due to the rising research and development activities for cancer treatment.

U.S. Clinical Oncology Next Generation Sequencing Market Segmentation

Grand View Research has segmented the U.S. clinical oncology next-generation sequencing market based on technology, workflow, application, end use:

U.S. Clinical Oncology Next Generation Sequencing Technology Outlook (Revenue, USD Million, 2018 - 2030)

• Whole Genome Sequencing

• Whole Exome Sequencing

• Targeted Sequencing & Resequencing Centrifuges

U.S. Clinical Oncology Next Generation Sequencing Workflow Outlook (Revenue, USD Million, 2018 - 2030)

• Pre-Sequencing

• Sequencing

• Data Analysis

U.S. Clinical Oncology Next Generation Sequencing Application Outlook (Revenue, USD Million, 2018 - 2030)

• Screening

  • Sporadic Cancer

  • Inherited Cancer

• Companion Diagnostics

• Other Diagnostics

U.S. Clinical Oncology Next Generation Sequencing End Use Outlook (Revenue, USD Million, 2018 - 2030)

• Hospitals

• Clinics

• Laboratories

List of Key Players in U.S. Clinical Oncology Next Generation Sequencing Market

• Illumina, Inc.

• Thermo Fisher Scientific

• F. Hoffmann-La Roche Ltd.

• Agilent Technologies

• Myriad Genetics

• Beijing Genomics Institute (BGI)

• Perkin Elmer

• Foundation Medicine

• Pacific Bioscience

• Oxford Nanopore Technologies Ltd.

• Macrogen, Inc.

• Qiagen