The global vaccine adjuvants market size is expected to reach USD 5.96 billion by 2033, registering a CAGR of 5.60% from 2026 to 2033, according to a new report by Grand View Research, Inc. The significance of adjuvant research in the development of vaccines has increased gradually due to inadequate immunogenicity of innovative vaccine antigens. In addition, the growing focus on long-lasting immunization effect against existing and emerging diseases is expected to boost the demand for vaccine adjuvants.
Furthermore, rising prevalence of cervical cancer is anticipated to boost the market. According to NCBI, around 15,000 females die every year due to cervical cancer. There are certain companies developing vaccine adjuvants for this type of cancer in order to enhance the efficacy, such as AS04 adjuvant-adsorbed (human papillomavirus vaccine) by GSK, which boosts the immune response for a longer duration.
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The particulate segment held the largest market share of 29.84% in 2025, primarily due to its strong ability to enhance both humoral and cellular immune responses, making vaccines more effective.
The infectious diseases segment accounted for the largest revenue share of 61.82% in 2025, driven by the increasing prevalence of viral and bacterial infections worldwide. Rising demand for vaccines against diseases such as influenza, hepatitis, and COVID-19 has significantly contributed to market growth.
The intramuscular segment held the largest revenue share of 33.78% in 2025, driven by its established use in delivering vaccines effectively and safely across diverse patient populations. This route allows efficient absorption of adjuvanted vaccines, leading to strong immune responses.
North America vaccine adjuvants industry dominated the global market in 2025 with the largest revenue share of 39.32%. This large share is attributed to its advanced vaccine development ecosystem and strong presence of leading pharmaceutical and biotechnology companies.
Grand View Research has segmented the global vaccine adjuvants market on the basis of type, application, administration, and region:
Vaccine Adjuvants Type Outlook (Revenue, USD Million, 2021 - 2033)
Pathogen
Adjuvant emulsion
Particulate
Combination
Others
Vaccine Adjuvants Application Outlook (Revenue, USD Million, 2021 - 2033)
Infectious diseases
Cancer
Others
Vaccine Adjuvants Administration Outlook (Revenue, USD Million, 2021 - 2033)
Oral
Intradermal
Intranasal
Intramuscular
Others
Vaccine Adjuvants Regional Outlook (Revenue, USD Million, 2021 - 2033)
North America
U.S.
Canada
Mexico
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
Australia
Thailand
South Korea
Latin America
Brazil
Argentina
Middle East and Africa
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players of Vaccine Adjuvants Market
GlaxoSmithKline plc.
Novavax, Inc.
Adjuvance Technologies, Inc.
SPI Pharma
Agenus, Inc.
CSL Limited
InvivoGen
Brenntag Biosector
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