Automated NGS Library Preparation Market To Reach $1,453.8 Million By 2030

Automated NGS Library Preparation Market Growth & Trends

The global automated NGS library preparation market size is anticipated to reach USD 1,453.8 million by 2030 and is projected to grow at a CAGR of 13.34% from 2025 to 2030, according to a new report by Grand View Research, Inc. The increasing demand for high-throughput sequencing and the need for efficient and reproducible sample preparation is driving the growth of automated NGS library preparation technologies. These advancements enhance workflow efficiency, minimize human errors, and provide scalability for various genomic applications, including clinical diagnostics, oncology research, and drug discovery.

The COVID-19 pandemic further accelerated the adoption of automated NGS library preparation solutions as laboratories worldwide sought streamlined and scalable sequencing workflows. The surge in genomic surveillance and infectious disease research during the pandemic emphasized the need for automation of sample preparation. Moreover, collaborations between research institutions, biotechnology companies, and healthcare providers led to significant technological advancements, boosting the market’s expansion.

In addition, the rising availability of automated NGS library preparation services has further fueled market growth. Contract research organizations (CROs) and Contract Manufacturing Organizations (CMOs) are essential in supporting the development and commercialization of sequencing-based applications. These service providers offer expertise in clinical trials, regulatory compliance, and scalable manufacturing, facilitating faster and more cost-effective deployment of automated NGS solutions. Automation is becoming increasingly essential as the demand for NGS expands across various fields.

However, integrating automation into NGS library preparation workflows can be complex, involving challenges like equipment compatibility, software integration, and protocol adaptation. It also requires training personnel to manage and maintain advanced systems. Despite these hurdles, successful implementation offers substantial benefits, including enhanced scalability, minimized errors, and increased throughput-positioning automation as a strategic investment for laboratories aiming to stay competitive in the fast-evolving genomics space.

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Automated NGS Library Preparation Market Report Highlights

• The kits & reagents segment accounted for the largest market revenue share in 2024, owing to their recurring demand, ease of use, and critical role in ensuring workflow consistency. The growing adoption of automated platforms further boosted reagent consumption. However, the instruments segment is expected to grow at the fastest CAGR over the forecast period.

• Based on type, the targeted genome sequencing segment led the market with the largest revenue share of 45.76% in 2024, driven by its cost-effectiveness, high accuracy, and growing use in clinical and diagnostic applications. On the other hand, the whole genome sequencing segment is anticipated to witness at the fastest CAGR of 14.58% over the forecast period.

• Based on workflow, the nucleic acid extraction segment accounted for the largest market revenue share in 2024, owing to its foundational role in sequencing protocols and the high demand for reliable, high-quality sample preparation across applications. On the other hand, the fragmentation segment is expected to grow at the fastest CAGR during the forecast period.

• Based on application, the drug & biomarker discovery segment accounted for the largest market revenue share in 2024. This is attributed to the rising use of NGS in precision medicine, target identification, and companion diagnostics development. However, the disease diagnostics segment is projected to grow at the fastest CAGR over the forecast period.

• Based on end use, the pharmaceutical and biotechnology companies segment accounted for the largest market revenue share in 2024. The growth is due to increased investment in genomics research, drug development, and the adoption of automated sequencing technologies to accelerate R&D workflows. On the other hand, the academic and research institutions segment is expected to register at the fastest CAGR during the projected period.

• North America dominated the market with the largest revenue share in 2024, owing to factors such as strong presence of key market players, advanced healthcare infrastructure, significant R&D investments, and high adoption of genomic technologies. Asia Pacific region is expected to grow at the fastest CAGR during the forecast period.

Automated NGS Library Preparation Market Segmentation

Grand view research has segmented the global automated NGS library preparation market based on product, type, workflow, application, end-use, and region:

Automated NGS Library Preparation Product Outlook (Revenue, USD Billion, 2018 - 2030)

• Instruments

• Kits & Reagents

  • DNA Library Preparation Kits

  • RNA Library Preparation Kits

  • Exome/Targeted Capture Library Preparation Kits

  • Others           

Automated NGS Library Preparation Type Outlook (Revenue, USD Billion, 2018 - 2030)

• Targeted Genome Sequencing

• Whole Genome Sequencing

• Whole Exome Sequencing

• Other Sequencing Types

Automated NGS Library Preparation Workflow Outlook (Revenue, USD Billion, 2018 - 2030)

• Nucleic Acid Extraction

• Fragmentation

• Adapter Ligation

• Purification & Quantification

Automated NGS Library Preparation Application Outlook (Revenue, USD Billion, 2018 - 2030)

• Drug & Biomarker Discovery

• Disease Diagnostics

  • Cancer Diagnostics

  • Reproductive Health Diagnostics

  • Infectious Disease Diagnostics

  • Other Disease Diagnostic Applications

• Others

Automated NGS Library Preparation End-use Outlook (Revenue, USD Billion, 2018 - 2030)

• Hospitals and Clinics

• Academic and Research Institutions

• Pharmaceutical and Biotechnology Companies

• Others

vRegional Outlook (Revenue, USD Billion, 2018 - 2030) 

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • Germany

  • UK

  • France

  • Italy

  • Spain

  • Sweden

  • Denmark

  • Norway

• Asia Pacific

  • China

  • Japan

  • India

  • South Korea

  • Australia

  • Thailand

• Latin America

  • Brazil

  • Argentina

• Middle East and Africa (MEA)

  • South Africa

  • UAE

  • Saudi Arabia

  • Kuwait

List of Key Players in the Automated NGS Library Preparation Market

• Illumina, Inc.

• Thermo Fisher Scientific Inc.

• Agilent Technologies, Inc.

• QIAGEN N.V.

• F. Hoffmann-La Roche Ltd

• Bio-Rad Laboratories, Inc.

• Revvity

• Oxford Nanopore Technologies Ltd.

• Pacific Biosciences of California, Inc.

• Hamilton Company