Transplant Box Market Size, Share & Trends Analysis Report By Application (Kidney, Liver, Heart, Lung, Others), By Region (North America, Europe, Asia Pacific, Latin America, MEA), And Segment Forecasts, 2024 - 2030

Transplant Box Market Size & Trends

The global transplant box market size was estimated at USD 155.51 million in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 8.6% from 2024 to 2030. Rising cases of multiple organ failure coupled with increasing incidence of chronic disorders, are the major factors driving the growth of market for transplant boxes. In addition, growing government and NGO initiatives to encourage organ donation are a few other factors contributing towards market growth. For instance, cardiovascular diseases have become one of the major causes of mortality and morbidity over the last three decades.

As per the reports published by British Heart Foundation in 2023, approximately 620 million people across the globe have heart and circulatory diseases, 200 million individuals have CHD (Coronary Heart Disease). Additionally, Centers for Disease Control and Prevention revealed that in 2022, 699.65 million people in U.S. died due to heart disease. Thus, escalating cases of cardiovascular disorders are anticipated to surge the rate of heart transplants, thereby propelling the market growth for transplant boxes.

The increasing prevalence rate of chronic liver ailments such as liver cirrhosis, end-stage liver disease, acute liver failure is also expected to boost market growth over the forecast period. For instance, as per the data published by United Network for Organ Sharing in 2022, over 42,800 organ transplants were performed in U.S. out of which 603 were liver transplants and 4,111 were heart transplants. Moreover, the geriatric population is more likely to suffer from organ failure.

Increasing geriatric patient population globally would boost the market growth for transplant boxes in the near future. For instance, as per the reports of WHO, around 80% of elderly people by 2050 will reside in nations with a low or middle income. In addition, it is anticipated that the number of persons 80 years of age or older will be reaching around 426 million by 2050. Moreover, growing geriatric population in the countries such as Japan, China, Italy, Germany, UK, and Brazil are expected to grow at the fastest rates in the shortest span of time in the future. For instance, according to WHO, China has one of the world's fastest-growing aging populations. Due to rising life expectancy and falling fertility rates, it is predicted that by 2040, 28% of China's population would be aged 60 or older.  Increasing elderly population is witnessing an increase in age-related organ failures and chronic health issues that might require organ transplants. This surge in demand for transplant boxes, crucial for the preservation and transportation of organs, is directly linked to the rising demand for organ transplantation in the elderly.

Additionally, growing government initiatives to promote organ donation are further anticipated to influence the market for transplant boxes over the forecast period. For instance, 13th Indian Organ Donation Day was held on 3rd August 2023, held by Union Health Minister Mansukh Mandaviya, India. The purpose of the ceremony was to raise awareness about dead organ donation. It was revealed that by 2023 India has more than 15,000 organ donors annually. To simplify and accelerate the process of transferring human remains from other nations to India, the International Health section of the Health Ministry established the eCARe portal (e-clearance of afterlife remains).

Market Concentration & Characteristics

The market growth stage is medium, and the pace of the market growth is accelerating. The transplant box market is characterized by a high degree of growth owing to rising cases of multiple organ failure coupled with increasing incidence of chronic disorders, and technology improvements.  Development of novel technologies that extend the preservation periods of organs, results in increased adaptability in logistics and transportation. This could involve adding advanced methods for controlling temperature, oxygenation, and organ monitoring.

Key strategies implemented by players in market are new product launches, expansion, acquisitions, partnerships, and other strategies. In January 2023, the U.S. FDA granted OrganOx premarket approval for its metra system, a completely automated normothermic machine perfusion (NMP) device for the transportation and preservation of donor livers intended for transplantation.

Degree of innovation in the market is characterized by a continuous emphasis on enhancing safety, efficiency, and preservation of organs during transplantation. In recent years, there has been a noticeable increase in the focus on creating portable and compact transplant boxes. These boxes make it simpler to transport organs from donors to recipients. Additionally, researchers have been investigating technological advancements, including the incorporation of machine learning and data analytics, to improve predictive capabilities and optimize protocols for preserving organs.

The market for transplant boxes is subject to regulatory approval to ensure the safety and efficacy of these medical devices. Regulatory bodies, such as the FDA, in U.S. or European Medicines Agency (EMA) in Europe, play a crucial role in evaluating and approving transplant boxes before they can be commercially available.

Regulatory bodies, such as health authorities and transplantation organizations, set forth stringent requirements regarding the materials, construction, and sterilization procedures of transplant boxes. These standards are designed to minimize the risk of contamination, infection, and damage to the organs during transportation, thereby upholding the success rates of transplantation procedures. Adherence to these regulations not only ensures the safety of the organs but also contributes to the overall effectiveness of transplant programs.

North America holds the largest market share, owing to factors such as factors like rising healthcare spending, a high number of surgeries, and increasing demand for safe and effective solutions to transport and preserve organs during transplantation procedures in this region contribute to this dominance in this region.  The dominance of the region is reinforced by the presence of leading manufacturers in this region. Moreover, countries such as China and Japan are major contributors to the Asia Pacific market due to increasing focus on organ transplantation procedures, rising awareness about the importance of organ donation, and advancements in medical infrastructure.

The market comprises the presence of several players with varying market shares and diverse product offerings which leads to a fragmented market scenario. Moreover, intense competition among existing players and the constant pursuit of innovation drives the introduction of new and improved transplant box solutions. As companies strive to differentiate themselves in terms of product features, quality, and compliance with standards, the market becomes more fragmented.

The market has witnessed significant growth and is expected to expand further across various regions in response to increasing healthcare demands. Manufacturers seeking regional expansion are focusing on tailoring transplant boxes to meet specific regional regulatory standards and climatic conditions. Collaborations with local healthcare institutions, government initiatives promoting organ donation, and investments in distribution networks also play a crucial role in expanding the market footprint.

Application Insights

Kidney segment led the market and accounted for 56.75% of the total revenue share in 2023. Increasing cases of Chronic Kidney Diseases (CKD) and subsequent kidney failures are expected to surge the kidney transplant rate driving the demand for transplant boxes. For instance, according to the Centers for Disease Control and Prevention in 2023, around 35.5 million of adults in the U.S. suffer from chronic kidney diseases every year. Also, the article published by National Library of Medicine in 2022 stated that over 800 million people worldwide suffered from CKD, a degenerative disease that affected more than 10% of the global population. Moreover, as per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) statistics, in the U.S., 25,499 kidney transplants were performed in 2022. Throughout the country, there were 88,658 patients waiting for kidney transplants by February 2023.

The segment is projected to witness the highest growth rate over the forecast period.Increasing cases of chronic diseases such as hypertension and diabetes drive the segment growth in near future. For instance, according to a report released by WHO in March 2023, approximately 1.28 billion people worldwide suffer from hypertension. The potential of developing Chronic Kidney Disease (CKD) increases with the increasing geriatric population. Reduced kidney function from age-related changes in the kidneys occurs due to aging. CKD is primarily caused by hypertension. The ability of the kidneys to filter waste products gets reduced due to uncontrolled high blood pressure, which damages the kidneys' blood vessels.

Additionally, Type 2 diabetes is a significant risk factor for CKD. Reduced kidney function can result from damage to the kidneys' tiny blood capillaries caused by high blood sugar levels. For instance, according to statistics collected by the Endocrine Society, approximately 33% of persons over the age of 65 were considered to have diabetes in January 2022. The number of kidney transplants is rising in accordance with the rising incidence of CKD patients. Kidney transplant is the most significant treatment for treating advanced-stage kidney disease. The increasing need for kidney transplants is the primary factor influencing the demand for transplant boxes.

Regional Insights

North America accounted for 47.49% of the global market in 2023 and is expected to continue its dominance over the forecast period. An important market driver is the aging population in North America. Age frequently increases the prevalence of urological diseases, increasing the need for transplant box. This is owing to the high prevalence of chronic kidney diseases and heart failure rates, as well as increasing investments for improving healthcare infrastructure, which are the major factors promoting market growth.

Increased organ failure risk due to the growing prevalence of chronic diseases in individuals increases the demand for transplant procedures, drives the market growth. For instance, according to the Canadian Cancer Society's 2022 data, 8,100 new cases of kidney and renal pelvis cancer were anticipated to be found in Canada in 2022.

U.S. Transplant Box Market Trends

The transplant market in the U.S. is expected to grow over the forecast period due to the increasing cases of liver cancer. For instance, as per the National Cancer Institute's published data, about 41,210 new cases of intrahepatic bile duct cancer and liver cancer were reported in the U.S. in 2023. Also, as per the data reported by United Network for Organ Sharing in 2023, 103,869 patients were on waiting list for organ transplant, and 38,761 organ transplant procedures were performed in U.S.

In addition, favorable healthcare reimbursement policies, high healthcare spending along with established R&D infrastructure, and huge demand for organ transplants are the factors driving the market for transplant boxes in this region.

UK Transplant Box Market Trends

The transplant box market in the UK is expected to grow over the forecast period due to the rising number of clinical studies and trials for the product approvals and novel product launch in this region.

France Transplant Box Market Trends

The transplant box market in France is expected to grow over the forecast period due to increasing healthcare expenditure along with well-established R&D infrastructure.

Germany Transplant Box Market Trends

The transplant box market in Germany is expected to grow over the forecast period owing to technological advancements aid in meeting and exceeding regulatory standards and quality requirements for transplant box in this region. Advanced transplant boxes are designed with a focus on compliance with healthcare regulations and international standards to ensure the safety and efficacy of organ transport.

The Asia Pacific region is anticipated to grow at the fastest CAGR over the forecast period. This is attributed to rising patient awareness of organ donation and rising healthcare costs. In addition, the market for transplant boxes is expected to be driven in upcoming years by the rising cost of healthcare, the growing elderly population, and the increasing frequency of chronic illnesses. Many individuals travel to Asia Pacific countries for medical care due to the affordable cost of surgical operations. As a result, the market for transplant boxes has grown significantly in the area due to a surge in medical tourism and an increase in chronic conditions that cause organ failure.

China Transplant Box Market Trends

The transplant box market in China is expected to grow over the forecast period owing to increasing number of organ donations due to increasing healthcare awareness about organ donations among the people in this region.

Japan Transplant Box Market Trends

The transplant box market in Japan is expected to grow over the forecast period owing to the collaborations between medical institutions and transport providers stands as a strategic imperative to optimize organ logistics, thereby enhancing operational efficiency within the healthcare sector.

Saudi Arabia Transplant Box Market Trends

The transplant box market in Saudi Arabia is expected to grow over the forecast period due to the increasing government initiatives for organ donation awareness.

 Kuwait Transplant Box Market Trends

The transplant box market in Kuwait is expected to grow over the forecast period due to rising healthcare expenditure, early disease diagnosis coupled with increasing incidence of chronic diseases.

Key Transplant Box Company Insights

The market for transplant boxes is undergoing significant changes that are transforming how organs are transported and transplanted. One crucial trend involves a growing emphasis on advanced materials and innovative designs to improve the efficiency and safety of organ transport. Leading companies in the field are making substantial investments in research and development to unveil transplant boxes that provide superior thermal regulation, secure protection for organs, and the ability to monitor conditions in real-time.

The advent of smart technologies is revolutionizing transplant boxes, incorporating features such as IoT-enabled monitoring systems and data analytics for real-time tracking of organ conditions during transportation. This technological integration enhances the overall safety and success rates of transplant procedures. These trends are prompting top players in the transplant box industry to adapt and evolve their product offerings and strategies. Established companies are engaging in strategic partnerships and collaborations with research institutions to stay at the forefront of technological advancements. Mergers and acquisitions are also observed as key players aim to consolidate their market positions and broaden their product portfolios. Regulatory compliance and adherence to quality standards are becoming increasingly crucial in this market. Top players are actively participating in the development of industry standards and regulations, ensuring that their products meet the stringent requirements for organ transportation.

Recent Developments

• In January 2024, Loyola Medicine achieved a significant milestone by successfully conducting its inaugural transplant using the TransMedics Organ Care System (OCS), affectionately known as "Heart-in-a-Box." This cutting-edge technology essentially serves as a miniature intensive care unit, ensuring the well-being and vitality of donor hearts. By maintaining them in a natural state that closely resembles the human body, the "Heart-in-a-Box" extends the organ's viability to an impressive 12 hours—twice the duration provided by traditional cold storage methods.

• In October 2023, Oregon Health & Science University launched a novel perfusion device Liver in the Box. The traditional method involved placing the liver on ice and setting up a short period of time for transplantation. A perfusion machine, as opposed to the ice approach, allows the organ to be preserved for up to 24 hours prior to transplantation by passing blood through it at room temperature.

• In May 2023, GenDx received global certification and approval from UNITO (Università degli Studi di Torino) for its cDNA assay which is used to monitor the organ rejections that occur in lung transplant procedures.

• In March 2023, Health Resources & Services Administration declared a modernization initiative to improve the organ procurement and transplantation network's integrity and transparency through several measures. Initiatives involve seeking Congress to make specific modifications to the National Organ Transplant Act, releasing updated statistics on organ donors and transplants, and giving emphasis to modernizing the OPTN IT system.

Transplant Box Market Report Scope

Global Transplant Box Market Report Segmentation

This report forecasts revenue growth at regional and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global transplant box market report based on application, and region:

• Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Kidney

  • Liver

  • Heart

  • Lung

  • Others

• Region Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Denmark

    • Sweden

    • Norway

  • Asia Pacific

    • Japan

    • China

    • India

    • Thailand

    • South Korea

    • Australia

  • Latin America

    • Brazil

    • Mexico

    • Argentina

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE

    • Kuwait