Terminal Sterilization Services Market Size, Share & Trends Analysis Report By Product (Ethylene Oxide, Irradiation), By End-use (Hospital & Clinics, Pharma & Nutraceuticals), By Region, And Segment Forecasts, 2025 - 2030

Terminal Sterilization Services Market Trends

The global terminal sterilization services market size was estimated at USD 13.09 billion in 2024 and is projected to grow at a CAGR of 11.08% from 2025 to 2030. The rising number of surgical procedures, growing incidences of hospital-acquired infections, rise in prevalence of chronic diseases, and rapid technological advancements are the major factors anticipated to drive market growth globally. For instance, as per a report by The Indian Express, in January 2024, an estimated 30 million surgical procedures are performed annually in India.

The increasing prevalence of healthcare-associated infections (HAIs) is a major driver for the market growth. HAIs, which are infections patients acquire during their stay in healthcare facilities, are a significant concern worldwide, leading to higher morbidity, extended hospital stays, and increased healthcare costs. To mitigate the risks of infections, healthcare facilities are investing more heavily in sterilization services to ensure that all medical devices and equipment are properly disinfected before use.

This is driving demand for effective and reliable sterilization methods such as Ethylene Oxide (EtO), irradiation, and steam sterilization. The focus on reducing HAIs is also encouraging healthcare providers to adopt advanced sterilization technologies that offer greater consistency and traceability, ensuring compliance with increasingly stringent infection control regulations. As the global burden of HAIs continues to rise, the need for effective terminal sterilization services is expected to grow, further propelling the market's expansion.

Moreover, the prevalence of chronic diseases is expected to increase the demand for terminal sterilization. For instance, as per the WHO, more than 40% of people aged 65 and above in the UK have reported at least one chronic disease, whereas 15% of people have at least two chronic diseases. Similarly, according to the CDC, in October 2024, each year, over 795,000 people in the U.S. experienced a stroke.

In addition, a surge in the geriatric population may increase the demand for terminal sterilization services. For instance, according to UNFPA data, in July 2024, the global proportion of people aged 65 and older has almost doubled, rising from 5.5% in 1974 to 10.3% in 2024. This share is expected to reach 20.7% by 2074, with the population aged 80 and above projected to more than triple. Geriatric people are more susceptible to acquiring HAIs; thus, to restrict their spread in the geriatric population, the use of terminal sterilization services has increased, further propelling market growth.

Market Concentration & Characteristics

The market exhibits a moderate level of innovation. While established techniques like steam sterilization, ethylene oxide (EtO) sterilization, and radiation sterilization remain foundational, ongoing advancements are evident. These include the development of novel sterilization methods like plasma and hydrogen peroxide vapor sterilization, process optimization for enhanced efficiency, advanced monitoring and control systems for consistent quality, and innovative packaging technologies for extended sterility.

The market has seen moderate M&A activity. Key players have strategically acquired specialized sterilization facilities to expand their service capacity and geographical reach. Mergers with complementary service providers broaden service offerings, while acquisitions of technology companies integrate advanced sterilization technologies into operations. These strategic moves aim to enhance market position and competitiveness.

Regulations significantly impact the market. Stringent standards enforced by regulatory bodies like the FDA and EMA ensure the safety and efficacy of medical devices and equipment. Compliance with these regulations is crucial, driving the need for robust quality control systems, rigorous documentation, and adherence to specific sterilization protocols.

While there are no direct substitutes for terminal sterilization services, alternative sterilization methods and in-house sterilization capabilities can be considered indirect substitutes. However, the complexity of sterilization processes, the need for specialized equipment, and stringent regulatory requirements often make outsourcing sterilization services to specialized providers a more cost-effective and reliable option.

The end-user concentration in the market varies across regions and healthcare sectors. In developed countries, the market is moderately concentrated, with a few large healthcare systems and medical device manufacturers dominating demand. In emerging markets, the end-user landscape is more fragmented, with numerous smaller healthcare facilities and medical device manufacturers contributing to the market.

Product Insights

The ethylene oxide segment dominated the market with the largest revenue share of 40.99% in 2024. This growth can be attributed to its effectiveness in sterilizing a wide range of heat-sensitive medical devices. Its ability to penetrate complex and porous materials, coupled with its efficacy against a broad spectrum of microorganisms, has made it a preferred choice for many healthcare providers. In addition, the well-established infrastructure of EtO sterilization facilities globally has contributed to its dominance.

The irradiation segment is anticipated to grow at the fastest CAGR from 2025 to 2030. This growth is primarily driven by the rising demand for sterile medical devices, increasing healthcare expenditure, and the growing awareness of infection control. Irradiation offers several advantages over traditional sterilization methods, such as its ability to penetrate deeply into materials, its effectiveness against a wide range of microorganisms, and its environmental friendliness. As the healthcare industry continues to prioritize patient safety and regulatory compliance, the demand for irradiation sterilization services is expected to surge, propelling the growth of this segment.

End-use Insights

The hospitals & clinics segment dominated the market in 2024 and is expected to witness the fastest growth over the forecast period. The increasing burden of HAIs is primarily boosting the demand for sterilization in hospitals and other healthcare settings. In addition, the growing number of surgical procedures and stringent safety guidelines for staff & patients in terms of medical waste disposal are likely to drive the adoption of terminal sterilization services in hospitals. For instance, according to the WHO, at any time, the prevalence of HAIs falls between 3.5% and 12% in developed countries. At the same time, every 10th person out of 100 in a hospital suffers from HAI. Usage of suitable disinfectants and sterilization methods is essential, as they can help prevent the transmission of infections.

Therefore, with the increasing number of HAIs, the use of terminal sterilization is expected to increase, thus propelling the market during the forecast period. Furthermore, the increasing number of surgical procedures in clinics is a major factor contributing to segment growth. Maintaining proper hygiene and sanitation is necessary to maintain a healthy environment in the clinic. 

Regional Insights

The North America terminal sterilization services market held the largest revenue share of 35.43% in 2024. This can be attributed to the region’s advanced healthcare infrastructure, high regulatory standards, and increasing focus on patient safety and infection control. With a strong presence of major healthcare facilities, medical device manufacturers, and pharmaceutical companies, the demand for reliable and compliant sterilization services is consistently high in North America.

U.S. Terminal Sterilization Services Market Trends

The U.S. terminal sterilization services market held the largest share in North American market in 2024. The growing incidence of HAIs and the increasing number of surgeries are among the factors anticipated to boost the demand for terminal sterilization services in the U.S. For instance, as per the Healthcare Information and Management Systems Society, each day, one out of 25 patients in the U.S. are affected with HAI. In addition, the rising number of surgeries in the U.S. is expected to boost the market, as terminal sterilization plays an important role in reprocessing surgical units.

Asia Pacific Terminal Sterilization Services Market Trends

The Asia Pacific terminal sterilization services market is set for significant growth, driven by several key factors such as the presence of numerous local players in countries such as China and Japan, as these companies introduce innovative products tailored to regional needs, increasing competition and accessibility. Additionally, the growing demand for reusable medical devices is also anticipated to propel the growth of the market for terminal sterilization services. Major market players are also making efforts to enter untapped markets such as India, China, and Korea, thereby expanding the market scope.

The terminal sterilization services market in China is expected to witness significant growth over the forecast period driven by substantial investments from both public and private sectors in research, technological advancements, and strong collaboration among various stakeholders, including healthcare professionals and universities. Furthermore, the increasing government initiatives coupled with rising healthcare expenditures are further expected to fuel the market growth.

Japan terminal sterilization services market is driven by a strong focus on quality and safety. The aging population and the increasing prevalence of chronic diseases are driving the demand for sterilization services.

Europe Terminal Sterilization Services Market Trends

Europe is recognized as one of the most advanced regions globally, characterized by its advanced technologies and infrastructure, which contribute to exceptional healthcare facilities and high-quality patient care. The increasing healthcare expenditure, and a rising prevalence of chronic diseases. The region has a well-established healthcare infrastructure and stringent regulatory standards, which contribute to the demand for effective sterilization services. Key trends shaping the market include the adoption of advanced sterilization technologies, increased outsourcing of sterilization services, and a growing focus on environmental sustainability. In addition, the increasing demand for minimally invasive surgeries and the rising use of reusable medical devices further propelling the market's growth.

The terminal sterilization services market in the UK is driven by stringent regulatory standards and a focus on patient safety. Increasing healthcare expenditure and a growing geriatric population are also contributing to market growth. Moreover, the increasing incidence of HAIs and the growing prevalence of chronic diseases are among the factors expected to positively impact the market over the forecast period.

France terminal sterilization services market is anticipated to witness significant growth over the forecast period owing to the increasing demand from the healthcare, pharmaceutical, and biotechnology sectors. As healthcare standards and regulations continue to tighten, there is a heightened focus on ensuring the sterility of medical and pharmaceutical products. This has led to more companies outsourcing sterilization to specialized service providers who can meet stringent regulatory requirements.

The terminal sterilization services market in Germany is driven by the strong healthcare system and a focus on technological advancements. The increasing prevalence of chronic diseases and the aging population are further fueling market growth. Moreover, Germany's stringent regulatory environment, coupled with high-quality standards in healthcare, creates a strong demand for reliable and effective sterilization services.

Latin America Terminal Sterilization Services Market Trends

The terminal sterilization services market in Latin America is witnessing growth due to increasing healthcare investments and an expanding pharmaceutical sector. Countries across the region are enhancing healthcare infrastructure and regulatory frameworks to meet international standards, which is raising the demand for specialized sterilization services.

MEA Terminal Sterilization Services Market Trends

The MEA terminal sterilization services market is expected to witness significant growth due to the region's growing healthcare needs and ongoing efforts to improve medical standards. Many countries in MEA are increasing their healthcare investments to address infectious diseases, rising chronic conditions, and a growing population, all of which contribute to a higher demand for sterilization services.

Key Terminal Sterilization Services Company Insights

Top market players are significantly investing in R&D activities to discover advanced solutions and increase their presence in the market. Emerging players in this market are focused on targeting specific clinical needs, which can offer them a competitive advantage in the market.

Key emerging companies in the market include:

• Microtrol Sterilization Services: A prominent player in India, Microtrol specializes in gamma irradiation and E-Beam sterilization services, catering to the growing healthcare sector.

• Avantti Medi Clear: Based in Mexico, Avantti Medi Clear offers a range of sterilization services, including EtO and gamma irradiation, serving the Latin American market.

Recent Developments

• In March 2023, Getinge announced the complete acquisition of Ultra Clean Systems Inc., a leading U.S. manufacturer of ultrasonic cleaning technologies. These technologies are widely used in hospitals and surgery centers for the decontamination of surgical instruments.

• In August 2023, STERIS plc announced the completion of its previously disclosed acquisition of the surgical instrumentation, laparoscopic instrumentation, and sterilization container assets from BD.

Terminal Sterilization Services Market Report Scope

Global Terminal Sterilization Services Market Report Segmentation:

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global terminal sterilization services market report based on the product, end-use, and region.

• Product Outlook (Revenue, USD Million, 2018 - 2030)

  • Ethylene Oxide

  • Irradiation

    • X-ray

    • Gamma (Co 60)

    • E-beam

    • Others

  • Moist Heat Terminal Sterilization

  • Others

• End-use Outlook (Revenue, USD Million, 2018 - 2030)

  • Hospitals and Clinics

  • Pharma and Nutraceuticals

  • Medical Device Manufacturing/Packaging

  • Other Manufacturing Sectors (Semiconductors, Food/Confectionaries, Chemical/Materials)

  • Academic Research Institutes

  • Others

• Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Italy

    • Spain

    • Denmark

    • Sweden

    • Norway

  • Asia Pacific

    • China

    • Japan

    • India

    • Australia

    • Thailand

    • South Korea

  • Latin America

    • Brazil

    • Argentina

  • Middle East and Africa

    • Saudi Arabia

    • South Africa

    • Kuwait

    • UAE