Renal Denervation Market Size, Share & Trends Analysis Report By Technology (Micro-Infusion, Ultrasound, Radiofrequency Based), By Region, And Segment Forecasts, 2024 - 2030

Renal Denervation Market Size & Trends

The global renal denervation market size was valued at USD 340.4 million in 2023 and is projected to grow at a CAGR of 40.2% from 2024 to 2030 owing to the rising prevalence of cardiovascular diseases, hypertension, and heart diseases. According to the World Health Organization, approximately 1.28 billion adults aged 30-79 years globally are affected by hypertension, with a significant portion of these individuals having uncontrolled blood pressure.

The growing burden of hypertension has led to an increased demand for effective treatment options, such as renal denervation. It is a minimally invasive procedure that disrupts nerve activity in the renal arteries to lower blood pressure. This treatment has the potential to provide an alternative therapeutic approach for patients suffering from resistant hypertension.

Technological advancements in renal denervation devices have also played a crucial role in market growth. Innovations such as catheter-based radiofrequency ablation and ultrasound-based systems have improved the safety and efficacy of the procedure, appealing both patients and healthcare providers. Companies such as Medtronic and Recor Medical have been at the forefront of these advancements, with their devices showing promising results in clinical trials.

Furthermore, the increasing investment in research and development activities has propelled the market growth. Companies have heavily invested in clinical trials to validate the efficacy and safety of renal denervation devices. For example, studies presented at the Transcatheter Cardiovascular Therapeutics (TCT) conference demonstrated that patients with resistant hypertension who underwent renal denervation experienced significantly lower blood pressure compared to those in placebo control groups

Technology Insights

Radiofrequency based technology dominated the market with a 74.6% share in 2023, primarily due to its effectiveness and advancements in treating resistant hypertension. Healthcare providers have preferred radiofrequency-based renal denervation owing to its proven efficacy in reducing blood pressure by targeting the renal nerves. Radiofrequency ablation works by delivering controlled energy to the renal artery walls, disrupting the sympathetic nerves that contribute to hypertension. This minimally invasive procedure has shown significant promise in clinical trials, leading to its increased adoption by healthcare providers. Furthermore, radiofrequency-based technology is one of the earliest methods developed for renal denervation and has a first-mover advantage. 

Ultrasound renal denervation is expected to register the fastest CAGR during the forecast period owing to its enhanced safety and efficacy compared to other methods. With its non-invasive nature, ultrasound energy can ablate renal nerves without direct contact with the arterial walls, reducing the risk of arterial damage and other complications. In addition, technological innovations including high-intensity focused ultrasound (HIFU) have improved the precision and effectiveness of the procedure. Furthermore, recent studies of clinical trials involving ultrasound-based systems have provided better outcomes. They had substantial effects on patients with resistant hypertension by reducing their blood pressure levels. These positive outcomes have stimulated demand from both physicians and patients. 

Regional Insights

The renal denervation market in North America was driven by technological advancements such as improved catheter designs and precise energy delivery systems. These have enhanced the procedure's safety and efficacy. In addition, key companies in the region have invested in R&D efforts to bring innovative products to the market. Their efforts are supported by favorable regulatory environments, with agencies including the FDA expediting the approval process for new renal denervation devices

U.S. Renal Denervation Market Trends

The U.S. renal denervation market was driven by the rise in healthcare infrastructure and investments. Technological advancements such as next-generation devices with improved safety and efficacy have fueled the market growth. Additionally, collaborations between medical device companies and healthcare providers to introduce innovative products in the market have been a major contributing factor. For instance, Mercator MedSystem’s micro-infusion-based renal denervation system delivers agents at a specific site to denervate the renal artery, thus reducing the blood pressure in patients.

Europe Renal Denervation Market Trends

Europe renal denervation market secured the dominant share with 45.6% of the global revenue in 2023 owing to the high prevalence of hypertension and cardiovascular diseases. According to the European Society of Cardiology, hypertension affects over 30% of the adult population in Europe, creating a substantial demand for effective treatment options. Renal denervation, being a minimally invasive procedure, offers a promising solution for patients with resistant hypertension who do not respond well to conventional medications.

Asia Pacific Renal Denervation Market Trends

Asia Pacific renal denervation market is expected to witness a significant growth rate over the forecast period. The region is anticipated to witness significant growth due to the increasing population with an alarming number of hypertension cases. Furthermore, the increasing investments in healthcare and growing government efforts in developing economies such as China, Japan, India, and South Korea have fueled the market growth.

Key Renal Denervation Company Insights

Some of the key companies in therenal denervation market include Medtronic,Abbott, Ablative Solutions, Inc.,Boston Scientific Corporation, and more. These organizations have undertaken several strategies such as R&D, mergers and acquisitions, and product launches to strengthen their market dominance.

• Medtronic is a medical technology services and solution-based company. The company’s portfolio includes devices for cardiac and vascular diseases, respiratory and neurological disorders, diabetes management, and surgical technologies. Medtronic has been at the forefront of developing renal denervation technology, a minimally invasive procedure aimed at treating resistant hypertension.

• Abbott is a healthcare company, known for its diverse portfolio of medical devices, diagnostics, nutritional products, and branded generic pharmaceuticals. The company has been involved in research and development activities of various innovative technologies. In addition, the company has conducted clinical trials on renal denervation systems.

Recent Developments

• In November 2023, Medtronic announced the U.S. FDA approval of their Symplicity Spyral renal denervation (RDN) system, known as the Symplicity blood pressure procedure, for the treatment of hypertension.

Renal Denervation Market Report Scope

Global Renal Denervation Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global renal denervation market report based on technology, and region.

• Technology Outlook (Revenue, USD Million, 2018 - 2030)

  • Radiofrequency based

  • Ultrasound based

  • Micro-Infusion based

• Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • Germany

    • UK

    • France

    • Spain

    • Italy

    • Sweden

    • Norway

    • Denmark

  • Asia Pacific

    • China

    • Japan

    • India

    • South Korea

    • Australia

    • Thailand

  • Latin America

    • Brazil

    • Argentina

  • Middle East and Africa (MEA)

    • UAE

    • South Africa

    • Kuwait

    • Saudi Arabia