Chiral Chromatography Columns Market Size, Share & Trends Analysis Report By Type, By Product (Pre-packed Columns, Empty Columns), By Material (Metal Based, Glass Based, Plastic Based), By End Use, By Region, And Segment Forecasts, 2024 - 2030

Market Size & Trends

The global chiral chromatography columns market size was estimated at USD 105.5 million in 2023 and is projected to grow at a CAGR of 4.3% from 2024 to 2030. Prominent factors facilitating the growth of the market are technological advancements in the chromatography instruments. For instance, in February 2022, Sartorius acquired Novasep’s chromatography division after receiving approval from the U.S. Federal Trade Commission. The acquired portfolio includes chromatography systems designed for smaller biomolecules such as, insulin, oligonucleotides, and peptides along with advanced systems for continuous biologics manufacturing.

Moreover, increasing R&D investments in the pharmaceutical and biotechnology industry is also fueling the market growth. Pharmaceutical and biotechnology companies are investing significantly in research to develop new protein-related products for healthcare needs. Technologies such as chromatography, radiopharmaceuticals and targeted therapies are crucial for protein separation and identification during drug discovery and development processes.

Drivers, Opportunities & Restraints

Developing economies including India, China, Brazil, and others offer high-growth opportunities for market players due to increasing research activities and adoption of analytical instruments. These countries present sustainable markets for life science instruments, driving the demand for chiral chromatography columns.

Additionally, the emphasis on environmentally friendly practices in chromatography, known as green chromatography, is creating growth avenues for market players. Green chromatography focuses on reducing waste generation, energy consumption, and hazardous chemicals used in chromatographic processes.

Furthermore, the growth of this sector is also driven by the cost-effective purification and process development of biological drugs. Additionally, the rapid expansion of the pharmaceutical, biotechnology, proteomics, and life science market through new product approvals and launches significantly influences the industry dynamics. For instance, in June 2022, Bio-Rad Laboratories, Inc introduced the CHT-prepacked Foresight Pro Columns to support chromatography applications in various stages of biological drug development and production. These prepacked columns come in a standardized design and format, providing a more cost-effective and flexible alternative to customer-packed options.

Type Insights

“The demand for high performance liquid chromatography columns type segment is expected to grow at a significant CAGR of 4.6% from 2024 to 2030 in terms of revenue”

High performance liquid chromatography (HPLC) dominated the market with the largest share of 49.2% in 2023. HPLC is primarily driven by the need for accurate and precise separation of components in complex mixtures. The ability to separate, identify, and quantify specific compounds is crucial in various industries such as pharmaceuticals, food, environmental analysis, and research. High-performance liquid chromatography (HPLC) systems are designed to handle a wide range of sample types with high sensitivity and resolution, making them essential tools for quality control, research, and development processes.

Moreover, the growing demand for automation and efficiency in analytical processes further fuels the segment growth. High Performance Liquid Chromatography Columns are becoming increasingly automated, allowing for higher throughput and reproducibility while minimizing manual intervention. This automation leads to improved productivity and reduced analysis time, making these systems indispensable in modern analytical laboratories.

Product Insights

“The demand for pre-packed columns segment is expected to grow at a significant CAGR of 4.5% from 2024 to 2030 in terms of revenue”

Pre-packed columns systems dominated the market with the largest share of 77.4% in 2023. The growth is driven by the convenience offered by these products, as pre-packed columns come ready-to-use and eliminate the need for users to pack their own columns with chiral stationary phases. This saves time and effort in method development and optimization, making them ideal for laboratories with high sample throughput requirements. These products also offer reproducibility, as pre-packed columns are manufactured under controlled conditions, ensuring consistent performance from column to column. This reliability is crucial for obtaining accurate and reliable results in chiral separations.

Moreover, technological advancements in pre-packed column with enhancement of performance help the market flourish. For instance, in March 2022, the machine learning model demonstrated exceptional predictive abilities for plate height and asymmetry, with the quality of packing being significantly impacted by backbone and functional mode. Therefore, the performance of prepacked columns is expected to have significant growth in the market with these new machine learning methods.

Material Insights

“The demand for metal based segment is expected to grow at a significant CAGR of 4.6% from 2024 to 2030 in terms of revenue”

The metal based segment accounted for 42.4% of the global revenue share in 2023. The most common metal used for the chromatography columns is the stainless-steel column. Inside the column thin layers of stationary phase are present. The high strength of the stainless steel can withstand the high pressure of pumps used in HPLC systems.

The plastic based segment is expected to grow at a significant CAGR of 4.4% over the forecast period. The segment is expected to witness growth over the forecast period owing to the cost-effectiveness of the chromatography column. The economical nature of the chromatography columns also exhibit advantages such as lightweight packing, and suitable for routine laboratory and academic analysis.

End Use Insights

“The environmental testing laboratories segment is expected to grow at a significant CAGR of 5.0% from 2024 to 2030 in terms of revenue”

The pharmaceutical & biotechnology segment accounted for 26.7% of the global revenue in 2023. Pharmaceutical processing involves quality control and checking, which is an integral part of the industry to ensure the product’s purity and viability. The growth in pharmaceutical production across the world is expected to drive the demand for the chiral chromatography columns market over the forecast period.

The environmental testing laboratories segment is anticipated to witness the fastest growth with a CAGR of 5.0% over the forecast period. The rising compliance in accordance with the regulations and codes, the demand for environmental testing for various industries is becoming essential which is likely to boost the growth of the choral chromatography column market over the forecast period.

Regional Insights 

North America chiral chromatography columns market dominated the global industry with a revenue share of 37.9% in 2023. The shift towards green chemistry in the region has led to a growing demand for chromatography instruments that support sustainable and environmentally friendly practices. Chromatography is a widely used technique for separating mixtures into their individual components, making it essential in various industries such as pharmaceuticals, biotechnology, food and beverage, environmental analysis, and more.

Moreover, the increasing demand for chiral separation chromatography columns driven by the adoption of green chemistry practices in North America is expected to have a ripple effect on the global market. As more vendors embrace sustainable solutions and environmentally friendly technologies, the market for chromatography instruments is anticipated to experience steady growth worldwide.

U.S. Chiral Chromatography Columns Market Trends

The chiral chromatography columns market in the U.S. held the largest share in 2023 in North America, owing to different factors, such as innovative developments, a significant rise in unique product approvals, and launches driving chromatography market growth. For instance, in June 2022, Tosoh Bioscience LLC, headquartered in Pennsylvania, USA, unveiled SkillPak 50 and SkillPak 200 pre-packed columns with inner diameters of 2.5 cm and 5.0 cm respectively. These columns are specifically crafted for the process development of monoclonal antibodies, antibody fragments, antibody-drug conjugates, oligonucleotides, and viruses.

Europe Chiral Chromatography Columns Market Trends

The chiral chromatography columns market in Europe is expected to witness lucrative growth over the forecast period. The growth is driven by the increasing adoption of pre-packed columns. Pre-packed columns offer a convenient solution for managing the time-consuming process of packing chromatography columns, which is particularly beneficial for industries and laboratories requiring efficient analytical volumes. The demand for prepacked columns is on the rise due to applications such as virus titer reduction testing, antibody purification, vaccine production, and recombinant protein purification. This trend is expected to continue dominating the European market for chiral chromatography columns as it provides a cost-effective and time-saving purification solution.

Asia Pacific Chiral Chromatography Columns Market Trends

The chiral chromatography columns market in Asia Pacific is driven by factors such as increasing research and development activities in pharmaceuticals, biotechnology, food and beverage, and environmental analysis sectors. The market is witnessing a shift towards advanced technologies and innovative products to meet the growing need for high-resolution separation techniques. Additionally, stringent regulations regarding drug safety and quality control are also contributing to the expansion of the chiral chromatography columns market in Asia Pacific. Companies operating in this market are focusing on strategic collaborations, product launches, and expansions to strengthen their market presence and cater to the diverse requirements of customers in the region.

Key Chiral Chromatography Columns Company Insights:

Some of the key players operating in the market include Agilent Technologies, Inc., GE Healthcare, Danaher, Thermo Fisher Scientific, Inc., among others.

• Veolia Water Technologies is an American company dealing in the space of life science and clinical research area. The company offers chromatography columns for HPLC and UPLC systems which include chiral chromatography columns.

• Danaher Corporation, a company based in Washington, U.S. dealing in biotechnology, diagnostics, and life sciences. The company offers chromatography columns via Life Science business across the world.

Daicel Corporation, Perkin Elmer, Bio-Rad Laboratories, are some of the emerging market participants in the chiral chromatography columns market.

• Perkin Elmer is a global company engaged in analytical instruments, and consumables for multiple markets. The company’s offering also includes chiral chromatography columns in pre-packaged format.

• Bio-Rad Laboratories is a manufacturer of pre-packed and empty chromatography columns. The company also deals in multiple markets related to life sciences research and clinical diagnostics field.

Recent Developments

• In May 2024, Advanced Materials Technology (AMT) launched its HALO Elevate C18, which represents a significant advancement in the field of high-performance liquid chromatography (HPLC). This new stationary phase offers exceptional high pH stability and selectivity, addressing key challenges faced by chromatographers in various analytical applications.

• In August 2023, Waters Corporation launched the XBridge Premier GTx BEH SEC columns specifically designed for gene therapy applications. These new columns are aimed at addressing the unique challenges faced in gene therapy research and development, offering high performance and reliability. 

Chiral Chromatography Columns Market Report Scope

Global Chiral Chromatography Columns Market Report Segmentation

This report forecasts revenue growth at global, regional & country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global chiral chromatography columns market report on the basis of type, product, material, end use, and region:

• Type Outlook (Revenue, USD Million, 2018 - 2030)

  • High Performance Liquid Chromatography Columns

  • Gas Chromatography Columns

  • Solid Phase Extraction Columns

• Product Outlook (Revenue, USD Million, 2018 - 2030)

  • Pre-packed Columns

  • Empty Columns

• Material Outlook (Revenue, USD Million, 2018 - 2030)

  • Metal Based

  • Glass Based

  • Plastic Based

• End Use Outlook (Revenue, USD Million, 2018 - 2030)

  • Pharmaceutical & Biotechnology

  • Academic & Research Institutes

  • Hospital and Diagnostic Clinics

  • Environmental Testing Laboratories

  • Food & Beverage Industry

  • Cosmetic

  • Nutraceutical

• Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

  • Asia Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

  • Latin America

    • Brazil

    • Argentina

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE