The U.S. Restricted Access Barrier System Market size is expected to reach USD 291.8 million by 2030, registering a CAGR of 7.0% from 2025 to 2030, according to a new report by Grand View Research, Inc. The market is primarily driven by the growth of the biotechnology industry in the U.S. due to technological advancements, an increasing number of small-scale biopharma companies, and rising investments in research.
Technological breakthroughs in biopharmaceutical and biotechnology manufacturing are expected to surge the market growth over the forecast period. The demand for modular equipment having the ability to reduce the time required for drug production and minimize the overall production cost is anticipated to provide a major boost to the market growth in the U.S.
The COVID-19 pandemic has reinstated the significance of collaborations; many life science companies are partnering among themselves to enhance R&D in the field of biotechnology. The pandemic has accelerated the need for sustainable development, energy conservation, and green pharmaceutical manufacturing, thereby influencing product development in the restricted access barrier systems (RABS) market.
A growing trend of contract development and manufacturing organization (CDMO) for aseptic manufacturing is expected to augment the demand for RABS. Contract manufacturers such as Aenova Group, DPT Laboratories, and Recipharm AB are focusing on new contracts in the U.S., in turn, positively impacting the market growth.
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The pharmaceutical segment dominated the market and accounted for the largest revenue share of 65.4% in 2024. This growth is attributed to the rising demand for aseptic production environments.
The chemical manufacturing segment is expected to grow at a CAGR of 7.2% over the forecast period, owing to the need to maintain aseptic conditions to prevent product contamination.
The U.S. government’s push for local pharmaceutical manufacturing, particularly for active pharmaceutical ingredients, has significantly augmented the need for RABS during production processes. This trend has led to an increase in aseptic manufacturing facilities across the nation.
Grand View Research has segmented the U.S. Restricted Access Barrier System Market on the basis of on application:
U.S. Restricted Access Barrier System Application Outlook (Revenue, USD Million, 2018 - 2030)
Pharmaceutical
Chemical Manufacturing
Medical
Others
List of Key Players in the U.S. Restricted Access Barrier System Market
I.M.A. Industria Macchine Automatiche S.P.A.
Germfree Laboratories, Inc.
Extract Technology
AZBIL TELSTAR, S.L.U.
Syntegon Technologies GmbH
Isolation Systems Inc.
Shanghai Tofflon Science and Technology Co., Ltd.
Ortner Reinraumtechnik GmbH
COMECER S.p.A.
SKAN AG
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