The global viral vector production (research-use) market size is expected to reach USD 3.9 billion by 2028, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 18.8% from 2021 to 2028. The expanding research base for advanced therapies has primarily driven the market for research applications including preclinical, clinical, and investigational studies.
The outbreak of the COVID-19 pandemic has created lucrative opportunities for the market players, particularly in the vaccine manufacturing sector. The application of viral vectors in vaccine development against SARS-CoV-2 has witnessed remarkable growth in the fiscal year 2020. By far, the manufacturing of viral vectors for research use is impeded by a lack of production capacity to fulfill the growing market needs.
Thus, operating key stakeholders are engaged in implementing new approaches to overcome these challenges and expand production capacities. The improving ratio of clinical success to the number of clinical trials of gene and cell therapy products is a testament to the enhancing manufacturing capabilities.
Currently, several new gene therapy products are in the late stages of development and the pipeline continues to expand across the globe. The forward momentum for the advanced therapy arena is anticipated to drive investment to conduct research for the development of safe viral vectors and therapies.
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Adeno-associated virus (AAV) accounted for the largest revenue share in 2020. Proven records of non-pathogenicity are one of the important key factors boosting the adoption of this segment
Recently, usage of AAV is rising considerably across several therapeutic areas, consequently witnessing a significant boost in adoption rate throughout the forecast period
In terms of revenue share, the downstream processing segment dominated the market in 2020 owing to highly complex polishing and purification procedures of final products
Furthermore, the growing demand for viral vectors due to their increased adoption as therapeutics has led to an increase in the need for optimizing downstream and upstream workflows
This is driving investment flow in both segments, resulting in a significant share of upstream processing
Given the extensive efforts in COVID-19 vaccine development, the application of viral vectors in the vaccine development segment has witnessed tremendous growth, resulting in the largest revenue share of this segment in 2020
The research institutes segment dominated the market in terms of revenue share in 2020. The increasing involvement of scientific communities in gene and cell therapy research has driven the revenue flow in this segment
North America captured the maximum revenue share in 2020 with the U.S. at the forefront
One major factor that has contributed to the larger share of this regional market is the presence of a substantial number of centers and institutes that are engaged in the R&D of advanced therapies
Investments made by the federal bodies for the expansion of cell therapy research base in the region are anticipated to enhance the growth of the market in North America
The key market players are engaged in collaboration with pharma companies to serve their viral-vector-based research needs pertaining to advanced therapy development
Grand View Research has segmented the global viral vector production (research-use) market on the basis of vector type, application, workflow, end-use, and region:
Viral Vector Production (Research-use) Vector Type Outlook (Revenue, USD Million, 2017 - 2028)
Adeno-associated virus (AAV)
Lentivirus
Adenovirus
Retrovirus
Others
Viral Vector Production (Research-use) Application Outlook (Revenue, USD Million, 2017 - 2028)
Cell & Gene Therapy Development
Vaccine Development
Biopharmaceutical and Pharmaceutical Discovery
Biomedical Research
Viral Vector Production (Research-use) Workflow Outlook (Revenue, USD Million, 2017 - 2028)
Upstream Processing
Vector Amplification & Expansion
Vector Recovery/Harvesting
Downstream Processing
Purification
Fill-finish
Viral Vector Production (Research-use) End-use Outlook (Revenue, USD Million, 2017 - 2028)
Pharmaceutical and Biopharmaceutical Companies
Research Institutes
Viral Vector Production (Research-use) Regional Outlook (Revenue, USD Million, 2017 - 2028)
North America
U.S.
Canada
Europe
Germany
U.K.
France
Italy
Spain
Asia Pacific
Japan
China
India
South Korea
Australia
Latin America
Brazil
Mexico
Middle East & Africa (MEA)
South Africa
Saudi Arabia
List of Key Players of Viral Vector Production (Research-use) Market
Merck KGaA
Lonza
FUJIFILM Diosynth Biotechnologies U.S.A., Inc.
Cobra Biologics Ltd.
Thermo Fisher Scientific
Waisman Biomanufacturing
Genezen
YPOSKESI
Advanced BioScience Laboratories, Inc. (ABL, Inc.)
Novasep Holding S.A.S
Orgenesis Biotech Israel Ltd (formerly ATVIO Biotech ltd.)
Vigene Biosciences, Inc.
General Electric Company (GE Healthcare)
CEVEC Pharmaceuticals GmbH
Batavia Biosciences B.V.
Biovion oy
Wuxi AppTec Co., Ltd.
VGXI, Inc.
Catalent Inc.
Miltenyi Biotec GmbH
SIRION Biotech GmbH
Virovek Incorporation
BioNTech IMFS GmbH
VIVEbiotech S.L.
Creative Biogene
Vibalogics GmbH
Takara Bio.
Cell and Gene Therapy Catapult
BlueBird Bio
Addgene, Inc.
Aldevron, L.L.C.
Audentes Therapeutics
BioMarin Pharmaceutical
RegenxBio, Inc.
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