Tissue Clearing Market Size To Reach $206.6 Million By 2030

Tissue Clearing Market Growth & Trends

The global tissue clearing market size is expected to reach USD 206.6 million by 2030, according to a new report by Grand View Research, Inc., exhibiting a CAGR of 9.24% from 2023 to 2030. The growing investments in research and development within the fields of neuroscience and cancer research is anticipated to attribute in the growth of the market. Moreover, the growing advancements in the biotechnology industry in developing countries is further driving the growth of the market over the forecast period.

The growing investments in studying tissues which include the brain tissues in 3D have spurred the expansion of 3D histology. This approach involves reconstructing tissue samples in 3D, enabling the study of tissue structure. It also enables the simultaneous analysis of cellular shape in a true 3D context along with precise omics data at a microscopic level. Tissue-clearing methods enhance tissue transparency by adjusting the refractive index. This aids 3D histology, enabling a detailed molecular-level understanding of tissue morphology and pathology. Tissues are normally opaque, hindering microscopy, but optical clearing agents make them transparent by reducing scattering.

In addition, iDISCO, based  on classic histology, translates staining from sections to whole tissues. It reveals multiple apoptotic neurons in sensory ganglia, aiding neuron studies. It detects split Caspase-3 in developing axons and images degenerating axons in adult brains effectively. iDISCO also supports volume imaging of labeled structures in complex tissues. It has two variants; the first uses conventional methanol dehydration but may quench labeled fluorescent proteins. The increasing adoption of technological advancements in tissue-clearing techniques are anticipated to impel the market growth over the forecast period.

However, stringent animal welfare laws, like  the UK's Animals (Scientific Procedures) Act 1986, streamline lab research with animals. This law demands a thorough evaluation of projects involving animals, including procedure specifics and animal types. Moreover, global initiatives like AAALAC accreditation and ethical review boards reinforce animal welfare. Thus, stringent guidelines pertaining to medical research with animals are anticipated to constrain the growth of the market.

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Tissue Clearing Market Report Highlights

• Based on product, the kits & reagents segment dominated the market with a share of 68.64% in 2022. This can be attributed to its role in simplifying the adoption of tissue clearing techniques, offering standardized solutions, ensuring efficiency, and catering to the diverse needs of researchers across various fields of study.

• Based on tissue type, the soft tissue segment dominated the market with a share of 81.71% in 2022 and is anticipated to grow at the fastest CAGR. This can be attributed to its clinical relevance, its role in medical research and drug development, advancements in imaging technologies, and the importance of soft tissue interactions that are vital to physiological functions.

• Based on application, the neurology segment dominated the market with a share of 36.30% in 2022. This was primarily due to an increase in the number of R&D initiatives in this field.

• Based on end-use, the academic research segment held the largest market share of 87.62% in 2022. This can be attributed to the increasing number of research activities undertaken by research institutions for the development of novel therapies in the fields of neuroscience and oncology.

• In 2022, North America dominated the market with a share of 44.47%, owing to the presence of major market players, and robust healthcare infrastructure. These are anticipated to boost the market for tissue clearing in the region over the forecast period.

• Some of the key players operating in the market are Logos Biosystems; Visikol, Inc.; LifeCanvas Technologies; Miltenyi Biotec; Bio-Techne; Abcam plc; ClearLight Biotechnologies, Inc.; FUJIFILM Corporation; Thermo Fisher Scientific, Inc.; and Corning Incorporated.

Tissue Clearing Market Segmentation

Grand View Research has segmented the global tissue clearing market based on product, tissue type, application, end-use, and region:

Tissue Clearing Product Outlook (USD Million; 2018 - 2030)

• Instruments

• Kits & Reagents

• Services

Tissue Clearing Tissue Type Outlook (USD Million; 2018 - 2030)

• Soft Tissue

• Hard Tissue

Tissue Type Application Outlook (USD Million; 2018 - 2030)

• Neurology

• Oncology

• Cardiology

• Others

Tissue Clearing End-use Outlook (USD Million; 2018 - 2030)

• Academic Research

• Industrial

Tissue Clearing Regional Outlook (USD Million, 2018 - 2030)

• North America

  • U.S.

  • Canada

• Europe

  • UK

  • Germany

  • France

  • Italy

  • Spain

  • Denmark

  • Sweden

  • Norway

• Asia Pacific

  • Japan

  • China

  • India

  • Australia

  • South Korea

  • Thailand

• Latin America

  • Brazil

  • Mexico

  • Argentina

• Middle East & Africa

  • South Africa

  • Saudi Arabia

  • UAE

  • Kuwait

List of Key Players in Tissue Clearing Market

• Logos Biosystems

• Visikol, Inc.

• LifeCanvas Technologies

• Miltenyi Biotec

• Bio-Techne

• Abcam plc

• ClearLight Biotechnologies, Inc.

• FUJIFILM Corporation

• Thermo Fisher Scientific, Inc.

• Corning Incorporated