Nucleic Acid Labeling Market To Reach $3.75 Billion By 2030

Nucleic Acid Labeling Market Growth & Trends

The global nucleic acid labeling market size is estimated to reach USD 3.75 billion by 2030, registering a CAGR of 7.3% from 2025 to 2030, according to a new report by Grand View Research, Inc. Technological advancements with respect to PCR, DNA sequencing, nanotechnology, and microfluidics are expected to help enhance the market potential in the near future. Additionally, nucleic acid labeling products are gaining significant momentum across diagnostic as well as therapeutic interventions associated with cancer disorders and genetic deformities, thereby elevating the market growth.

Technologies that enable direct detection of specific sequences of RNA or DNA serve as occasional potent alternatives to amplification protocols employed in gene expression studies. Research activities performed on these lines have also led to the development of novel label protocols such as that of incorporating probes that are specifically labeled with anti-label antibodies conjugated via alkaline phosphatase. This direct detection technique employing the use of specific labeled probes has emerged as a reliable and flexible approach for gene expression analysis, well-suited for high-throughput screening.

The continuing quest for designing labels with enhanced functional properties suitable for hybridization assays has led to the introduction of an array of potential approaches to label nucleic acids that are inclusive of genes encoding enzymes, microparticles, and a novel class of fluorophores.

With the emergence of novel viral infections, such as the coronavirus (COVID 19), followed by the MERS outbreak in 2015 and the SARS outbreak in 2003, healthcare professionals are experiencing a significant urge for the development of rapid detection approaches that can assist in the identification of target viruses at scale. The COVID-19 pandemic has also led to an increase in demand for nucleic acid-based research efforts aimed at developing breakthrough treatment solutions, further expected to accelerate market expansion.

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Nucleic Acid Labeling Market Report Highlights

• By product, the reagents segment is expected to grow at a significant CAGR over the forecast period. This is attributed to the fact that reagents are essential components across both enzymatic and chemical labeling, resulting in an expanding vendor base aimed at introducing novel and effective reagents to label DNA/RNA

• By labeling type, the radioactive or radioisotope labels dominated the market in 2024 and are anticipated to maintain their lead throughout the forecast period. Radioactive labeling is gaining increased traction among the professionals, which is further supplemented by the ease of incorporation of radioactively labeled nucleic acid sequences

• North America captured the largest share of 39.8% in 2024, which is primarily attributed to the expanding portfolios of emerging manufacturers, along with robust support from research organizations, collectively contributing to the regional revenue.

Nucleic Acid Labeling Market Segmentation

Grand View Research has segmented the global nucleic acid labeling market based on product, type, method, application, end-use, and region:

Nucleic Acid Labeling Product Outlook (Revenue, USD Million, 2018 - 2030)

• Kits

• Reagents

Nucleic Acid Labeling Type Outlook (Revenue, USD Million, 2018 - 2030)

• Radioisotope/Radioactive Labelling

• Non-radioactive Labelling

Nucleic Acid Labeling Method Outlook (Revenue, USD Million, 2018 - 2030)

• Enzymatic

  • TdT

  • T4 RNA Ligase

  • T4 PNK

  • DNA Polymerase

  • Others

• Chemical

  • Periodate

  • EDC

  • Nonspecific Crosslinkers

Nucleic Acid Labeling Application Outlook (Revenue, USD Million, 2018 - 2030)

• Sequencing

• Microarray

• In Situ Hybridization

• Blotting Techniques

• Polymerase Chain Reaction

• Others

Nucleic Acid Labeling End-use Outlook (Revenue, USD Million, 2018 - 2030)

• Pharmaceutical & Biotechnology Companies

• Hospitals & Diagnostic Centers

• Academic & Research Institutes

• Others

Nucleic Acid Labeling Regional Outlook (Revenue, USD Billion, 2018 - 2030)

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • UK

  • Germany

  • France

  • Italy

  • Spain

  • Denmark

  • Sweden

  • Norway

• Asia Pacific

  • Japan

  • China

  • India

  • Australia

  • South Korea

  • Thailand

• Latin America

  • Brazil

  • Argentina

• Middle East & Africa

  • South Africa

  • Saudi Arabia

  • UAE

  • Kuwait

List of Key Players in the Nucleic Acid Labeling Market

• PerkinElmer

• F. Hoffmann-La Roche Ltd

• GE Healthcare

• Thermo Fisher Scientific Inc.

• Promega Corporation

• New England Biolabs

• Enzo Biochem Inc.

• Vector Laboratories, Inc.

• Merck KGaA

• Agilent Technologies, Inc.