The global mRNA therapeutics contract development & manufacturing organization market size is expected to reach USD 8.35 billion by 2030, registering a CAGR of 11.28% from 2024 to 2030, according to a new report by Grand View Research, Inc. Growing technological advancements in mRNA and cellular delivery systems, coupled with their cost effectiveness, manufacturing simplicity, and ability to target previously undruggable pathways, have limitless potential to revolutionize medicine. This could represent lucrative growth opportunities for the market. Increasing R&D investments to develop mRNA therapeutics and a strong product pipeline are also propelling the market’s growth. For instance, Moderna shared that R&D expenses for the fourth quarter of 2023 increased by 16% to USD 1.4 billion compared to the same quarter of 2022.
The R&D spending was driven by increased clinical manufacturing activities, with the company’s Cytomegalovirus (CMV) vaccine, RSV vaccine, and combination vaccine against COVID-19 & flu, as well as its individualized neoantigen therapy. Such factors are expected to boost research efforts in mRNA therapeutics. In addition, developing novel therapeutics to address unmet medical needs is altering the product market. The rise in molecular complexity drives the need for in-depth knowledge in research and manufacturing services, as well as the technology to enable sustainable expression and scale-up of novel molecular formats. Platform technologies, such as those for bioconjugation or the creation of bispecific antibodies, can drastically shorten development and production times, and customers are looking for skilled CDMOs who can assist them shorten the time to market and reducing investment risk. Consequently, the need for CDMOs to design and produce goods for the pharmaceutical and biotechnology industries is growing exponentially.
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The viral vaccines segment dominated the market with a share of 100.00% in 2023. Growth in the segment can be attributed to the rising availability and launch of various vaccines for the treatment of viral infection (COVID-19)
The infectious diseases segment held the largest market share in 2023 due to the growing incidence of infectious diseases, several advantages of mRNA vaccine over conventional vaccines, emerging clinical studies & pipeline analysis, and increasing collaboration between pharmaceutical companies & CDMO for production
The biotech companies end-use segment dominated the market and accounted for a share of more than 60.00% in 2023. The segment growth is driven by increasing strategic initiatives, such as partnerships & collaborations with CDMOs, to manufacture mRNA vaccines
Asia Pacific is expected to register the fastest growth rate of 10.83% from 2024 to 2030. Due to the rising number of pharmaceutical companies and contract manufacturing organizations in developing countries like India and China, Asia Pacific is likely to overtake Europe and North America in the near future
Grand View Research has segmented the global mRNA therapeutics contract development & manufacturing organization market based on application, indication, end-use, and region:
mRNA Therapeutics CDMO Application Outlook (Revenue, USD Million, 2018 - 2030)
Viral Vaccines
Protein Replacement Therapies
Cancer Immunotherapies
mRNA Therapeutics CDMO Indication Outlook (Revenue, USD Million, 2018 - 2030)
Infectious Diseases
Metabolic & Genetic Diseases
Cardiovascular & Cerebrovascular Diseases
mRNA Therapeutics CDMO End-use Outlook (Revenue, USD Million, 2018 - 2030)
Biotech Companies
Pharmaceutical Companies
Government & Academic Research Institutes
mRNA Therapeutics CDMO Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
Canada
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
South Korea
Australia
Indonesia
Latin America
Brazil
Mexico
Argentina
Middle East and Africa (MEA)
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in the mRNA Therapeutics Contract Development & Manufacturing Organization Market
Danaher (Aldevron)
Biomay AG
Bio-Synthesis, Inc.
eTheRNA
Kaneka Eurogentec S.A.
TriLink BioTechnologies
ApexBio Technology
BioNTech SE
Biocina
Lonza
Recipharm AB.
Novo Holdings (Catalent, Inc.)
Samsung Biologics
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