The global gRNA market size is anticipated to reach USD 1.62 billion by 2030 and it is projected to grow at a CAGR of 18.6% from 2024 to 2030, according to a new report by Grand View Research, Inc. The rising adoption of Next-Generation Sequencing (NGS) is significantly boosting the market. As NGS technologies become more prevalent, they empower researchers and scientists with advanced capabilities for genomic analysis and manipulation. NGS enables high-throughput sequencing of genetic material, allowing for the rapid and cost-effective examination of entire genomes. This efficiency is crucial for gRNA applications, as it facilitates the identification and validation of target genes for genetic manipulation. NGS technologies provide a precise and comprehensive understanding of genomic sequences. This precision is vital for designing gRNAs with high specificity, ensuring accurate targeting of genes during the gene editing process using CRISPR/Cas systems.
Furthermore, the increasing investments by biotechnology and pharmaceutical companies for R&D activities are expected to fuel the market in the coming years. The development of user-friendly and affordable gRNA synthesis kits and services has made CRISPR-Cas9 technology more accessible to researchers of all levels. The continuous discovery of novel applications for CRISPR-Cas9 fuels the demand for gRNA.
Additionally, the launch of new gRNA final products can drive innovation, expand the market reach of players, and accelerate the adoption of gene editing technologies, contributing to the overall growth & advancement of the market. For instance, in October 2023, Synthego, a prominent provider of genome engineering solutions, launched IND-enabling (INDe) gRNAs. This transformative offering marks a significant advancement in the CRISPR-based cell and gene therapy preclinical pipeline. By providing researchers with high-quality gRNAs meticulously designed for GLP-regulated preclinical and IND-enabling studies, this product incorporates comprehensive IND-compliant materials and documentation throughout its design and production. Thus, it will drive the market growth.
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On the basis of product & services, the product segment accounted for the largest revenue share of 73.4% in 2023. These products offer high accuracy, efficiency, and specificity in gene editing, making them popular among researchers is one of the primary drivers driving market expansion
On the basis of gRNA type, the research-use segment dominated the market share in 2023. A large number of research programs conducted across various research institutes demand research-grade gRNA is driving up demand for this segment
On the basis of application, the genome engineering segment dominated the market share in 2023. This growth can be attributed to the increasing demand for advanced genetic tools for research and therapeutic purposes
On the basis of end-use, the pharmaceutical & biotechnology companies segment dominated the market share in 2023. The adoption of gRNA in precision medicine by pharmaceutical and biotech companies fuels its market growth as it becomes integral to the development of personalized therapies
North America dominated the global industry in 2023 with a revenue share of 52.6% owing to the presence of key market players in the region. The majority of the key companies in this region have been actively involved in R&D activities involving gRNA
Grand View Research has segmented the global gRNA market based on product & services, gRNA type, application, end-use, and region.
gRNA Product & Services Outlook (Revenue, USD Million, 2018 - 2030)
Products
gRNA Final Products
gRNA Synthesis Products
gRNA Synthesis Kits
Plasmids
Others
Custom gRNA Synthesis Services
gRNA Type Outlook (Revenue, USD Million, 2018 - 2030)
Research-Use
GMP-grade
gRNA Application Outlook (Revenue, USD Million, 2018 - 2030)
Genome Engineering
Disease Model Studies
Functional Genomics
Epigenetics
Others
gRNA End-use Outlook (Revenue, USD Million, 2018 - 2030)
Pharmaceutical & Biotechnology Companies
Academic Research Institutes
CMOs & CROs
gRNA Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
Canada
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
China
Japan
India
Australia
Thailand
South Korea
Latin America
Brazil
Mexico
Argentina
Middle East & Africa
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in the gRNA Market
Thermo Fisher Scientific Inc.
Agilent Technologies Inc.
System Biosciences, LLC.
Jena Bioscience GmbH
Merck KGaA
GENEWIZ (Azenta Life Sciences)
Takara Bio Inc.
Synbio Technologies
Horizon Discovery Ltd.
Synthego
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