The global GLP-1 receptor agonist market size is expected to reach USD 156.71 billion by 2030, expanding at a CAGR of 17.46% from 2025 to 2030, according to a new report by Grand View Research, Inc. The strong product pipeline and formulation advancements are driving the market. In addition, novel innovative products are booming the market. In September 2019, Rybelsus, the first and only oral GLP-1 analog was approved by the U.S.FDA for improving the glycemic control in type-2 diabetes patients. It is a semaglutide-based product developed by Novo Nordisk, which is currently under review by European Medicines Agency (EMA) and Pharmaceuticals and Medical Devices Agency (PMDA). After receiving the approval, the market may witness significant growth over the forecast period.
Furthermore, pharmaceutical companies are focusing on research collaborations for developing new GLP-1 products. For instance, in September 2018, Eli Lilly and Company entered into a license agreement with Chugai Pharmaceutical Co., Ltd for OWL833. OWL833 is Chugai’s proprietary oral GLP-1 agonist candidate and as per the agreement Eli Lilly will obtain global commercialization and development rights.
The companies are currently aiming on geographical expansion for increasing the sales output. Novo Nordisk is expanding its business by investing in the manufacturing unit located in North Carolina. The company holds around 50.0% of the market share of GLP-1 receptor agonists and is expected to dominate the market over the forecast period. Furthermore, in July 2018, Sanofi invested about USD 74.1 million in China for establishing an R&D hub to enhance its global reach.
The companies are also focusing on getting approval for other indications like obesity and major adverse cardiovascular events by authorities like the U.S.FDA, EMEA, and others for the existing products to increase their life cycle. For instance, in January 2020, Novo Nordisk received the U.S. FDA approval for Ozempic for Major Adverse Cardiovascular Events (MACE) in type 2 diabetes patients.
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The ozempic segment dominated the market and accounted for a share of 34.17% in 2024. Ozempic is a brand-name U.S. FDA-approved prescription drug used to treat adults with type 2 diabetes.
Zepbound is expected to grow at a significant CAGR from 2025 to 2030. This growth can be attributed to its worldwide approval of a drug and high demand due to its high efficacy and tolerability.
The type 2 diabetes mellitus segment dominated the market in 2024 and is expected to grow at a CAGR of 17.06% over the forecast period.
The parenteral segment held the largest share in 2024 and is expected to grow at a CAGR of 17.42% from 2025 to 2030.
The hospital pharmacies segment held the largest share of 55.09% in 2024. The growth of hospital pharmacies has facilitated the integration of several healthcare components, increased inpatient visits for diabetes and obesity consultations, and improved customer convenience in acquiring GLP-1 medications.
North America GLP-1 receptor agonist market accounted for a 77.72% share in 2024. Established brands including liraglutide (Victoza), dulaglutide (Trulicity), exenatide (Byetta/Bydureon), and semaglutide (Ozempic) dominate the GLP-1 receptor agonist market in North America.
Asia Pacific GLP-1 receptor agonists market is anticipated to witness the fastest growth in the global market. The region's growing healthcare sector, sizable target population, and high unmet clinical needs are some factors projected to provide significant growth potential.
Grand View Research has segmented the global GLP-1 receptor agonist market report based on the product, application, route of administration, distribution channel, and region:
GLP-1 Receptor Agonist Product Outlook (Revenue, USD Million, 2018 - 2030)
Ozempic
Trulicity
Mounjaro
Wegovy
Rybelsus
Saxenda
Victoza
Zepbound
Other Products
GLP-1 Receptor Agonist Application Outlook (Revenue, USD Million, 2018 - 2030)
Type 2 Diabetes Mellitus
Obesity
GLP-1 Receptor Agonist Route Of administration Outlook (Revenue, USD Million, 2018 - 2030)
Parenteral
Oral
GLP-1 Receptor Agonist Distribution Channel Outlook (Revenue, USD Million, 2018 - 2030)
Hospital Pharmacies
Retail Pharmacies
Online Pharmacies
GLP-1 Receptor Agonist Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
Canada
Mexico
Europe
Germany
UK
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
China
Japan
India
South Korea
Australia
Thailand
Latin America
Brazil
Argentina
Middle East and Africa (MEA)
South Africa
Saudi Arabia
Kuwait
UAE
List of Key Players in the GLP-1 Receptor Agonist Market
Eli Lilly and Company
Sanofi
Novo Nordisk A/S
AstraZeneca
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