The global gene delivery technologies market size is expected to reach USD 10.27 billion by 2030, expanding at a CAGR of 11.4% from 2024 to 2030, according to a new report by Grand View Research, Inc. Technological advancements in viral vectors, a growing pipeline of advanced therapies, and a rising number of regulatory approvals for advance therapy products are some key driving forces of the market.
Several novel tools are being introduced for genetic alterations that have facilitated the scientific community to delineate the disease intricacies at the genomic level, leading to the emergence of novel gene delivery approaches. Furthermore, ongoing research to develop clinically relevant vectors including viral and non-viral vectors to combat chronic illnesses such as cancer, Alzheimer’s, and others through advanced therapies is spurring the market revenue.
An increase in investment and financing in the space to support the research, development, and manufacturing of various modes of gene transfer further accelerates the revenue growth. Currently, around 70% of gene and cell therapy programs are based on viral vectors leading to organic revenue growth for biological delivery technologies. The operating players are investing significantly to scale up their viral vector manufacturing capability and meet the growing demand.
Considering growing opportunities in physio-chemical gene delivery approaches, key players are making focused efforts to boost their business presence. For instance, nanoparticles have proven their efficiency as promising vehicles for clinical usage owing to their tunable morphology, and biological behaviors. Such ongoing developments in the space are anticipated to accelerate revenue growth in this market in the coming years.
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The wide implementation of biological gene delivery technologies in clinical usage owing to their high efficiency and specificity has resulted in the segment’s largest revenue share in 2023
Gene therapy development is the key revenue-generating application in the 2023 market owing to constantly expanding pipeline programs of therapies against life-threatening conditions coupled with the recent success of CAR-T therapies
The recent pandemic of SARS-CoV-2 has also resulted in substantial global investments in R&D of viral vector-based vaccine to combat the virus, resulting in lucrative growth of this segment
The ex vivo method accounted for the major revenue share owing to its advantages such as high transduction efficiency and less immunogenic responses
However, both in vivo and ex vivo have shown clinical success in the treatment of chronic conditions, thus both segments are expected to witness lucrative growth in the coming years
Given the high number of biotech companies and a favorable regulatory environment in the U.S.; North America dominated the global market in terms of revenue
On the other hand, Asia Pacific is projected to grow at the fastest pace during the forecast period
Constantly evolving CDMO and viral vector manufacturing landscapes through plant expansions and new sites being built across the Asian countries is spurring the adoption of vectors in this region
The key players are engaged in collaboration with therapy developers to support their product development process
Grand View Research has segmented the global gene delivery technologies market based on basis of mode, application, method, and region:
Gene Delivery Technologies Mode Outlook (Revenue, USD Million, 2020 - 2030)
Biological
Adenovirus
Retrovirus
AAV
Lentivirus
Other viruses
Non-viral
Chemical
Physical
Gene Delivery Technologies Application Outlook (Revenue, USD Million, 2020 - 2030)
Gene Therapy
Cell Therapy
Vaccines
Research
Gene Delivery Technologies Method Outlook (Revenue, USD Million, 2020 - 2030)
Ex vivo
In vivo
In vitro
Gene Delivery Technologies Regional Outlook (Revenue, USD Million, 2020 - 2030)
North America
U.S.
Canada
Mexico
Europe
Germany
U.K.
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
Australia
South Korea
Thailand
Latin America
Brazil
Argentina
Middle East Africa (MEA)
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in Gene Delivery Technologies Market
Thermo Fisher Scientific Inc.
Horizon Discovery Ltd.
QIAGEN
Oxford Biomedica PLC
OriGene Technologies, Inc.
SignaGen Laboratories
Promega Corporation.
SIRION BIOTECH GmbH
Flash Therapeutics
Takara Bio Inc.
Bio-Rad Laboratories, Inc.
F. Hoffmann-La Roche Ltd
System Biosciences, LLC.
Catalent, Inc.
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