Circulating Tumor Cells Market To Reach $24.96 Billion By 2030

Circulating Tumor Cells Market Growth & Trends

The global circulating tumor cells market size is estimated to reach USD 24.96 billion by 2030, expanding at a CAGR of 12.2% from 2025 to 2030, according to a new report by Grand View Research, Inc. This is attributed to rising prevalence of cancer worldwide, increasing demand for non-invasive cancer diagnostic tools, and advancements in circulating tumor cells (CTC) technologies.

In recent years, CTCs are increasingly used for determining the prognosis of cancer and helping clinicians decide the type of therapy required for cancer treatment. CTCs have wide applications in several areas of cancer management—early detection of cancer, risk assessment of cancer recurrence, guidance for therapies, and continuous monitoring of a patient during cancer treatment. The development of various tumor markers utilizing CTCs, which can be used to diagnose or monitor cancer, is expected to boost the adoption of CTCs over the forecast period. Therefore, it can be concluded that the detection of CTCs in the peripheral blood of patients with cancer acts as a promising diagnostic tool. For instance, quantitation and genomic profiling of CTCs enables cost-effective & accurate noninvasive monitoring of prostate cancer. The detection of CTCs is predictive for survival of cancer patients.

The limited applicability of these cells in rare cancers has hampered revenue growth to a certain extent. Circulating tumor cells are not applicable to tumors characterized by EpCAM negativity or low expression, such as neurogenic cancers. For instance, there is negligible evidence for the characterization of circulating tumor cells for sarcoma. Conversely, numerous methods are being studied for the isolation of these cells, which include methods based on epithelial antigen-targeted antibodies, anticipating to overcome these challenges in the near future.

However, in recent years, there has been a push for practical application, largely as a result of a wave of large players centralizing the technology through acquisitions and numerous partnerships with pharmaceutical firms to advance the formation of a value chain and speed up the CTC market’s growth. For instance, in June 2023, to develop a novel test for the detection of tumor cells that metastatic cancers shed into the blood, the University of Washington School of Medicine collaborated with RareCyte, Inc., which is a biotech company headquartered in Seattle. In addition, according to the research, the understanding of the circulating tumor cells in the bloodstream can track the changes in tumor cells, thus optimizing the treatment.

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Circulating Tumor Cells Market Report Highlights

• Based on technology, The CTC detection and enrichment methods segment accounted for the largest revenue share of 40.92% in 2024 owing to the increased availability of products for CTC enrichment and isolation as well as high usage and product penetration across the globe

• CTC analysis is expected to register the fastest CAGR during the forecast period due to the growing application potential of CTC analysis for investigational research, drug development, and biomarker studies

• Based on application, the research segment dominated the market in 2024 and it is expected to witness the fastest CAGR from 2025 to 2030

• Kits & reagent dominated the product segment in 2024, and it is expected to witness the fastest growth in forecast period of 2025-2030

• Based on specimen, the blood segment dominated the market in 2024. The other body fluids segment is expected to witness the fastest CAGR from 2025 to 2030

• Based on end-use, the research & academic institutes segment dominated the market in 2024 due to increasing focus on research and development activities for cancer diagnosis and treatment

• North America dominated the CTC market in 2024, owing to factors such as the presence of key market players Bio-Techne Corporation, Precision Medicine Group LLC, Epic Sciences, APPLIED DNA SCIENCES, INC., and LungLife AI, Inc. and the growth in pharmaceutical & biotechnology research sectors in this region

• Asia Pacific is expected to register the fastest CAGR over the forecast period due to several companies expanding their presence in countries like Japan 

Circulating Tumor Cells Market Segmentation

Grand View Research has segmented the global circulating tumor cells market based on technology, application, product, specimen, end use, and region:

Circulating Tumor Cells Technology Outlook (Revenue, USD Billion, 2018 - 2030)

• Circulating Tumor Cells CTC Detection & Enrichment Methods

  • Immunocapture (Label-based)

    • Positive Selection

    • Negative Selection

  • Size-based Separation (Label-free)

    • Membrane-based

    • Microfluidic-based

  • Density-based Separation (Label-free)

  • Combined Methods

• CTC Direct Detection Methods

• CTC Analysis

Circulating Tumor Cells Application Outlook (Revenue, USD Billion, 2018 - 2030)

• Clinical

  • Risk Assessment

  • Screening and Monitoring

• Research

  • Cancer Stem Cell & Tumorogenesis Research

  • Drug/Therapy Development

Circulating Tumor Cells Product Outlook (Revenue, USD Billion, 2018 - 2030)

• Kits & Reagents

• Blood Collection Tubes

• Devices or Systems

Circulating Tumor Cells Specimen Outlook (Revenue, USD Billion, 2018 - 2030)

• Blood

• Bone Marrow

• Other Body Fluids

Circulating Tumor Cells End Use Outlook (Revenue, USD Billion, 2018 - 2030)

• Research and Academic Institutes

• Hospital and Clinics

• Diagnostic Centers

Circulating Tumor Cells Regional Outlook (Revenue, USD Billion, 2018 - 2030)

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • Germany

  • UK

  • France

  • Italy

  • Spain

  • Sweden

  • Denmark

  • Norway

• Asia Pacific

  • China

  • Japan

  • India

  • South Korea

  • Australia

  • Thailand

• Latin America

  • Brazil

  • Argentina

• Middle East and Africa (MEA)

  • South Africa

  • UAE

  • Saudi Arabia

  • Kuwait

List of Key Players in Circulating Tumor Cells Market

• QIAGEN

• Bio-Techne Corporation

• Precision Medicine Group, LLC.

• Bio-Rad Laboratories, Inc.

• Natera, Inc.

• Illumina, Inc.

• Cell Microsystems

• Greiner Bio One International GmbH

• Ikonisys Inc.

• Miltenyi Biotec

• Creative Bioarray

• BioFluidica

• Abnova Corporation

• Biolidics Limited

• Creatv MicroTech, Inc.

• LungLife AI, Inc.

• Epic Sciences

• Rarecells Diagnostics

• ScreenCell

• Menarini Silicon Biosystems

• APPLIED DNA SCIENCES, INC.

• Sysmex Corporation

• STEMCELL Technologies, Inc.