The global cell lysis and disruption market size is expected to reach USD 9.63 billion by 2030, registering a CAGR of 8.7% from 2023 to 2030, according to a new report by Grand View Research, Inc. The anticipated revenue growth is attributed to accelerating the adoption of cell lysis and disruption methods during downstream processing to manufacture bio-therapeutics and other animal-based recombinant products. Technological developments in procedures involved in releasing cellular organelles have paved the way for the higher adoption of cell disruption methods.
As retrieval and purification of biopharmaceuticals involve cell disruption, a rise in demand for biopharma would lead to the subsequent growth of the market. In addition, advancements in the field of proteomics, metabolomics, and personalized medicine are expected to fuel progressive changes in this sector. However, the high costs of equipment coupled with the dearth of skilled professionals are expected to restrain revenue generation to a certain extent. The restraint can be addressed as the government organizations are releasing substantial funds to support development in the biotechnology sector.
Enzymatic lysis, owing to higher biological specificity, is likely to register the fastest CAGR over the forecast period. Manufacturers are embracing the trend of providing synthetic enzymes and pre-formulated kits, which can be used for the extraction and purification of proteins, DNA, and RNA. Sonication instruments in the products available are expected to witness lucrative growth due to higher adoption rates as a result of the reliability on these instruments. Factors attributing to this reliability include complete control allowed on parameters and negligible maintenance.
Among the physical methods, the high product yield obtained by sonication of the liquid sample is attributed to the larger revenue share of the ultrasonic homogenization method/technique. Asia Pacific will be the fastest-growing regional market from 2021 to 20285 due to lucrative opportunities offered by emerging nations, which has attracted investments from global firms in the region. Key companies are engaged in new product development and strategic alliances to maintain their market share.
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A rise in the development of biologics has subsequently led to high demand for better bioprocess solutions
The reagents & consumables segment is the most widely used segment, and it is estimated to advance at a significant CAGR during the forecast period
The advantages include an unaltered biological activity of the sample of interest and ideal compatibility with the laboratory reagents
Therefore, key players have developed different detergent-based solutions and buffers, to provide the best possible results for particular tissue types
Mammalian cell culture systems have grabbed substantial attention among biopharmaceutical manufacturers, thus leading to higher demand for cell lysis protocols for the same
The pharmaceutical & biotechnology companies segment accounted for the largest market revenue share of 36.5% in 2022
Substantial research in the development of nucleic-acid derived products is expected to drive progress in this application in the coming years
Grand View Research has segmented the global cell lysis and disruption market report based on technique, product, cell type, application, end-use, and region:
Cell Lysis And Disruption Technique Outlook (Revenue, USD Million, 2018 - 2030)
Reagent-based
Detergent
Enzymatic
Physical Disruption
Mechanical Homogenization
Ultrasonic Homogenization
Pressure Homogenization
Temperature Treatments
Cell Lysis And Disruption Product Outlook (Revenue, USD Million, 2018 - 2030)
Instruments
High Pressure Homogenizers
Sonicator
French Press
Microfluidizer
Bead Mill
Other Instruments
Reagents & Consumables
Enzymes
Detergent Solutions
Ionic Detergent
Nonionic Detergent
Zwitterionic Detergent
Kits & Reagents
Cell Lysis And Disruption Cell Type Outlook (Revenue, USD Million, 2018 - 2030)
Mammalian Cell
Bacterial Cell
Yeast/Algae/Fungi
Plant Cell
Cell Lysis And Disruption Application Outlook (Revenue, USD Million, 2018 - 2030)
Protein Isolation
Downstream Processing
Cell Organelle Isolation
Nucleic Acid Isolation
Cell Lysis And Disruption End-use Outlook (Revenue, USD Million, 2018 - 2030)
Academic And Research Institutes
Hospitals And Diagnostic Labs
Cell Banks
Pharmaceutical And Biotechnology Companies
Cell Lysis And Disruption Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
Canada
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
Australia
Thailand
South Korea
Latin America
Brazil
Mexico
Argentina
Middle East & Africa
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players of Cell Lysis And Disruption Market
Thermo Fisher Scientific, Inc.
Merck KGaA
Bio-Rad Laboratories, Inc.
F. Hoffmann-La Roche Ltd.
QIAGEN
Danaher
Miltenyi Biotec
Claremont BioSolutions, LLC
IDEX
Parr Instrument Company
Covaris, LLC
Cell Signaling Technology, Inc.
Qsonica
BD
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