The global biological skin substitutes market size is expected to reach USD 579.08 million by 2030 and is expected to expand at a CAGR of 8.88% from 2025 to 2030 based on a new report by Grand View Research, Inc. The increasing prevalence of skin diseases, rising incidence of chronic diseases & trauma emergencies, and increasing consciousness regarding tissue engineering, along with potential pipeline products, are some of the major factors responsible for the growth of tissue nano transfection technology. Furthermore, increasing government and private organizations’ investment in research and development activities is likely to boost the demand for biological skin substitutes.
The COVID-19 pandemic has affected several aspects of the wound care process, which includes compliance with wound care visits, triggering alternative approaches such as the use of virtual care platforms or telemedicine and streaming videos on the social media platform to assist the patients with wound dressing and empowering a do-it-yourself wound dressing approach. There is an increasing desire to understand how the social dimensions of health impact the Quality of Life (QoL) and effectiveness of wound care patients. The direct consequence of such changes in health care is the disruption of the continuity of wound care in several ways. However, these changes have negatively impacted wound outcomes but also have driven the development of a virtual-based approach for patient visits.
The key companies in the market are attempting to improve their portfolio by upgrading their products, employing significant cooperative efforts, and considering acquisitions and government permissions to increase their client base and capture a larger share of the biological skin substitutes market.
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Based on type, the human donor tissue-derived products segment accounted for the largest market share of 67.42% in 2024 as it allows better integration and acceptance by the patient's body
Based on application, the chronic wounds segment is expected to witness the fastest growth, with a CAGR of 9.13% over the forecast period due to the increasing prevalence of chronic wounds
Based on end-use, the hospital segment dominated the biological skin substitutes market with a revenue share of 54.97% in 2024. The outpatient facilities segment is expected to witness the fastest CAGR of 8.9% over the forecast period owing to the shorter wait times and more flexible scheduling options
North America accounted for the largest revenue share of nearly 41.25% in 2024 owing to the presence of major companies in the region
Grand View Research has segmented the global biological skin substitute market report based on the type, application, end use, and region:
Biological Skin Substitute Type Outlook (Revenue, USD Million, 2018 - 2030)
Human Donor Tissue-derived Products
Acellular Animal-derived Products
Biological Skin Substitute Application Outlook (Revenue, USD Million, 2018 - 2030)
Acute Wounds
Chronic Wounds
Biological Skin Substitute End Use Outlook (Revenue, USD Million, 2018 - 2030)
Hospitals
Outpatient Facilities
Research & Manufacturing
Biological Skin Substitute Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
Canada
Mexico
Europe
Germany
UK
France
Italy
Spain
Norway
Denmark
Sweden
Asia Pacific
Japan
China
India
Australia
South Korea
Thailand
Latin America
Brazil
Argentina
Middle East and Africa (MEA)
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in Biological Skin Substitute Market
Organogenesis Inc.
Integra LifeSciences Corporation
Smith+Nephew
Tissue Regenix
MIMEDX Group, Inc.
Essity Aktiebolag (publ))( Essity Health & Medical)
Stryker
Vericel Corporation
3M
BioTissue
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