1. Anticipated Impact Of GLP-1 Medications On PAP Devices For Obstructive Sleep Apnea (OSA):
In June 2024, phase III SURMOUNT-OSA trial data from Eli Lilly highlights the potential of GLP-1s in managing OSA. The trial compared the efficacy of GLP-1s alone and in combination with positive airway pressure (PAP) over 12 months. The combination therapy showed a 62.8% reduction in apnea-hypopnea index (AHI), compared to a 55.0% reduction with GLP-1 alone.
Factor |
Current Impact |
Anticipated Change |
AHI Reduction (PAP + GLP-1) |
62.8% |
Increase in combination therapy adoption |
AHI Reduction (GLP-1 alone) |
55.0% |
Improved awareness is expected to drive more diagnoses |
Stock Impact (ResMed) |
-6% |
Stabilization and potential growth |
Patient Propensity to Start PAP |
10.5% higher in GLP-1 users |
Expected to further increase |
A recent market analysis revealed that while overall GLP-1 use is increasing, it reached only few among patients considered candidates for a specific medical device. In addition, device use within this GLP-1 using population dropped only slightly, resulting in an overall impact on device use of less than 1%.
|
2020 GLP-1 Initiation |
2021 GLP-1 Initiation |
2023 GLP-1 Initiation |
|||
% of total |
Device Uptake 2020-present |
% of total |
Device Uptake 2020-present |
% of total |
Device Uptake 2020-present |
|
Precursor patients with GLP-1 |
7%
|
62% |
10% |
59% |
12% |
57% |
Precursor patients without GLP-1 |
93% |
65% |
90% |
65% |
88% |
65% |
Weighted Average |
|
65% |
|
64% |
|
64% |
Market dynamics: Initial demand for PAP devices is expected to remain stable, but long-term demand may decline as patients experience improved OSA symptoms and reduced dependency on these devices.
2. Increasing Product Recalls:
Product recalls are currently trending in the respiratory devices market, particularly due to recent high-profile incidents involving major manufacturers.
Impact On Respiratory Devices Industry
Phillips: In June 2021, Philips announced a recall of certain ventilators, bi-level positive airway pressure impacting over 15 million devices in the U.S. In 2021, the company recorded a 23% decline it its Connected Care business segment revenue owing to the impact of COVID-19 and significant impact of Respironics product recalls.
ResMed: The Philips recall had a positive impact on ResMed's financial performance, as it led to increased demand for ResMed's respiratory devices. ResMed capitalized on the market gap, significantly boosting its revenue. In fiscal year 2022, ResMed's revenue reached nearly $3.6 billion, with continued growth into fiscal year 2023. The company reported its highest-ever quarterly revenue of $1.03 billion in Q2 FY2023, a 16% increase year-over-year.
Baxter International: In July 2024, Baxter issued an urgent medical device recall for its Life2000 ventilator due to potential battery charger dongle damage. The recall leads to disruptions in sales, increased costs related to device replacements, and potential loss of customer trust, which could adversely affect the company's financial performance.
3. Competitive Landscape In The Respiratory Device Market:
Companies are increasingly exiting the respiratory devices market as part of strategic refocusing efforts. They may choose to divest from less profitable segments to concentrate on core businesses or more lucrative markets.
Exit Players |
Exit Market |
Key Updates |
Market Impact |
Philips Respironics |
Oxygen Concentrator & Mechanical Ventilator |
|
|
Invacare Corporation |
Oxygen Concentrator |
|
|
Medtronic |
Mechanical Ventilator |
|
|
Strategic innovation opportunities: The exit of Philips creates both challenges and opportunities for other market players, prompting innovation in response to home care provider needs. Companies like GCE Healthcare are stepping in with new product offerings to fill gaps in the market.
Optimistic scenario for competitors: The exit of Respironics open lucrative opportunity for companies like GCE Healthcare, Inogen, CAIRE, DeVilbiss, and Rhythm Healthcare to strengthen their market position and financial performance by pursuing strategic initiatives.
4. Other Ongoing Trends In The Respiratory Devices Industry
AI-driven innovations in respiratory devices market
The ongoing trends in the respiratory devices industry are heavily influenced by the integration of AI and advanced diagnostics. The quantitative growth in market penetration, investment, and early detection rates underscores the transformative impact these innovations are expected to have on respiratory care, leading to more effective treatments and cost savings in healthcare.
GE Healthcare
ICU Medical (Smiths Medical)
React Health
Medtronic
Fisher & Paykel Healthcare
ResMed
CAIRE, Inc. (Acquired by Niterra Co., Ltd. formarly known as NGK SPARK PLUG CO., LTD.);
Linde
Mindray
Chart Industries
Drägerwerk AG & Co. KGaA
Drive DeVilbiss International
Inogen, Inc.
Novartis International AG
Hamilton Medical.
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