Capillary Electrophoresis Market Size, Share & Trends Analysis Report By Product (Instrument, Consumables) By Mode (Capillary Zone Electrophoresis, Capillary Gel Electrophoresis), By Application, By End-use, By Region, And Segment Forecasts, 2024 - 2030

Capillary Electrophoresis Market Trends

The global capillary electrophoresis market size was estimated at USD 353.59 million in 2023 and is expected to grow at a CAGR of 5.38% from 2024 to 2030. This growth is attributed to increasing prevalence of chronic diseases, increasing use in increasingly utilized in drug discovery, pharmacokinetics, and biomarker identification, coupled with rising need for personalized medicines and technological advancements are major factors driving the market. Furthermore, increasing R&D spending in drug discovery and development and rising number of clinical laboratories are likely to drive the market over the forecast period.

Capillary electrophoresis (CE) is increasingly utilized in drug discovery, pharmacokinetics, and biomarker identification due to its high resolution, sensitivity, and ability to separate complex mixtures of biomolecules. As pharmaceutical companies focus on precision medicine and personalized therapies, CE plays a crucial role in understanding molecular interactions and disease mechanisms. For instance, the CAPILLARYS 3 OCTA by Sebia is an advanced automated capillary electrophoresis system. It builds on the CAPILLARYS 2 FLEX-PIERCING and shares technology with the CAPILLARYS 3 TERA. It offers a wide range of assays for conditions such as myeloma, diabetes, hemoglobinopathies, and chronic alcohol abuse. Key benefits include a flexible and scalable platform, smart reagent management, advanced piloting software, and high throughput with up to 79 results per hour. It handles multiple sample types, including whole blood, urine, and serum.

Increasing prevalence of chronic diseases such as cardiovascular disorders, diabetes, and various types of cancer are driving demand for CE's. As it has high resolution and ability to separate complex mixtures of biomolecules such as proteins, nucleic acids, and carbohydrates make it invaluable in identifying disease-specific markers that traditional methods may overlook. In clinical settings, CE facilitates the detection and quantification of biomarkers indicative of chronic diseases like cardiovascular disorders, diabetes, and various types of cancer. The technique allows for rapid and accurate profiling of patient samples, aiding in early diagnosis, disease monitoring, and personalized treatment strategies.

Technological advancements in electrophoresis systems. The shift towards minimally invasive diagnostics and point-of-care testing further drives the adoption of CE technologies. In addition, Recent technological innovations by manufacturers in capillary coatings, detection systems (e.g., fluorescence detection, mass spectrometry coupling), and automation have improved CE's throughput, sensitivity, and reproducibility. For instance, in September 2021, Sciex Company launched the BioPhase8800, a cutting-edge capillary electrophoresis system, which enables biological characterization during biopharmaceutical therapy. This innovative device allows for the simultaneous analysis of eight samples and features a multi-capillary design for Capillary Electrophoresis Sodium Dodecyl Sulfate (CE-SDS) applications. These advancements reduce analysis time and enhance data accuracy, making CE more attractive for high-throughput screening and routine laboratory applications.

The capillary electrophoresis market is further characterized by presence of several key players such as Agilent Technologies, Thermo Fisher Scientific, and PerkinElmer. These companies focus on product innovation, strategic collaborations, and mergers/acquisitions to expand their product portfolios and enhance market presence. Additionally, emerging companies and startups are introducing niche capillary electrophoresis systems targeting specific applications or technological enhancements, contributing to market dynamism.

Governments initiatives and increasing funding and substantial investments are driving the market, further research organizations worldwide are allocating significant funds towards biotechnology and life sciences research, which includes investments in capillary electrophoresis technologies. Funding initiatives aim to accelerate research in areas such as genomics and proteomics, thereby driving market growth. Government funding programs support research initiatives focused on advancing capillary electrophoresis technologies. Funds are directed towards basic research, applied sciences, and translational research aimed at improving healthcare outcomes, environmental monitoring, and agricultural sciences. These investments play a crucial role in driving technological innovations and expanding the utility of capillary electrophoresis across diverse fields.

Product Insights

The consumables segment accounted for largest revenue share of 71.0% in 2023 is also anticipated to grow at the fastest rate of 5.78% CAGR over the forecast period. This high growth is attributable due to the fact that they are essential for the regular operation and maintenance of CE systems. These include capillaries, reagents, buffers, and sample vials, which need frequent replacement to ensure optimal performance and accurate results. The continuous need for consumables creates a steady revenue stream for manufacturers, making them a significant market driver. Additionally, advancements in consumable technologies, such as enhanced sensitivity and specificity of reagents, further propel the growth and adoption of CE systems across various applications in diagnostics, pharmaceuticals, and research.

Novel capillary coatings are being explored to enhance separation efficiency, resolution, and reproducibility in CE. These include dynamic coatings that are added to the running buffer as well as covalently bonded static coatings on the inner capillary surface. Manufacturers are introducing dynamically coated capillaries for easier method development. Such as PVA-coated capillaries from Agilent Technologies.

Instrument segment is anticipated to witness significant growth over the forecast period. The capillary electrophoresis instruments market is driven by advancements in biotechnology, pharmaceutical research, clinical diagnostics, and food safety. Key instruments include Beckman Coulter PA 800 Plus, Agilent 7100, SCIEX CESI 8000 Plus, Bio-Rad BioFocus 2000: These systems address the need for precise and efficient analytical techniques.

Mode Insights

The capillary gel electrophoresis segment dominated the market and accounted for the largest share of 48.48% in 2023. The increasing advancements in CGE are enabling more efficient protein characterization, purity analysis, and aggregate detection crucial for the development and quality control of biopharmaceuticals. Integrated CGE platforms with streamlined workflows and higher sample throughput are increasing the productivity and efficiency of electrophoresis-based analyses. Furthermore, making capillary electrophoresis more feasible for academic, clinical, and commercial laboratories. Thus, driving the adoption of capillary electrophoresis systems in the pharmaceutical and biotechnology industries. Further, innovations such as microchip-based CGE and automated platforms are further expanding its applications and market adoption, ensuring continuous growth and technological evolution in this segment.

The capillary electrochromatography segment is anticipated to grow at the fastest rate over the forecast period. Owing to its unique ability to combine high efficiency with enhanced selectivity, making it particularly valuable for complex sample analysis. The technique's growth is further propelled by increasing demand in pharmaceutical research, proteomics, and environmental monitoring. Technological advancements, such as improved column materials, miniaturization, and integration with mass spectrometry, are expanding CEC's capabilities and applications. The push for more sensitive and specific analytical methods in drug development, personalized medicine, and forensic science is also contributing to CEC's adoption. Additionally, the technique's low sample and solvent requirements align well with the growing emphasis on sustainable and cost-effective laboratory practices.

Application Insights

The nucleic acid analysis segment dominated the market and accounted for the largest share of 31.11% in 2023. The global incidence of genetic disorders, cancer, and infectious diseases has been escalating in recent years. Genetic alterations in an individual's DNA can cause devastating conditions like thalassemia, sickle cell anemia, and cystic fibrosis. By analyzing nucleic acids, researchers provide valuable insights into these diseases. The rapid development of cost-effective, point-of-care testing kits and streamlined laboratory procedures for COVID-19 diagnosis has accelerated innovation in diagnostics, leading to a new wave of diagnostic advancements. In January 2 023, QIAGEN announced the launch of the EZ2 Connect MDx platform for the purification of DNA and RNA from 24 samples in parallel in under 30 minutes via its automated sample processing method to be used in diagnostic labs. Furthermore, in September 2021, Thermo Fisher Scientific announced expansion of nucleic acid testing kit manufacturing in India, capitalizing on the versatility of these tools beyond COVID-19 testing. The company's innovative kits can process up to 96 samples within just 30 minutes, showcasing their speed and efficiency.

The protein analysis segment is anticipated to grow at the fastest CAGR over the forecast period. The ability of capillary electrochromatography to provide high-resolution separation and quantification of proteins, including post-translational modifications and complex mixtures, makes it invaluable. Recent advancements in CE technology, such as improved detection methods and automation, have enhanced its accuracy and efficiency. These innovations meet the growing demand for detailed protein characterization, driving significant market expansion in this segment.

End-use Insights

The research organizations and institutes segment dominated the end use segments with the largest market share of 53.05% in 2023. Research organizations and institutes play a crucial role in advancing the capillary electrophoresis (CE) market. They drive innovation by developing new methodologies and applications for CE, enhancing its capabilities in fields like genomics, proteomics, and clinical diagnostics. These entities often collaborate with industry leaders to translate scientific discoveries into commercial products, fostering technological advancements. Additionally, they provide critical validation and standardization of CE techniques.

The pharmaceutical and biotechnology companies segment is anticipated to grow at a substantial rate. The pharmaceutical and biotechnology companies have a profound impact on the capillary electrophoresis (CE) market, driving innovation, demand, and application development. These industries are major end-users of CE technology, particularly in drug discovery, quality control, and biopharmaceutical analysis. Their substantial R&D investments and need for high-resolution, high-throughput analytical techniques push the boundaries of CE capabilities. The growing focus on biologics, personalized medicine, and stringent regulatory requirements has further increased CE adoption in areas like protein characterization, impurity profiling, and chiral separations. Pharmaceutical companies method development efforts often set industry standards, while their global presence influences CE market trends globally.

Regional Insights

North America dominated the market and accounted for a 35.44% share in 2023. This high share is attributable to increasing prevalence of chronic diseases in the region, coupled with the rising demand for personalized medicine in North America, as the need for precise and individualized treatment options. Capillary electrophoresis (CE) systems play a crucial role in this field due to their ability to analyze complex biological samples quickly and accurately. Key players in the region are involved in strategic initiatives such as product launches, mergers and acquisitions to cater to wide range of clientele.

U.S. Capillary Electrophoresis Market Trends

The market in the U.S. is expected to grow substantially over the forecast period. Increasing demand in pharmaceutical research, clinical diagnostics, and forensic applications. The market is expected to continue expanding due to technological advancements and growing adoption in various fields. Capillary electrophoresis (CE) has significantly improved disease diagnosis accuracy in the U.S. by providing a rapid, high-throughput, and sensitive analytical technique. Government support through funding for biotechnology research further propels the market.

Europe Capillary Electrophoresis Market Trends

Europe market was identified as a lucrative region in this industry. Owing to advancements in biotechnology and increasing demand for precise diagnostic tools. This growth is fueled by applications in clinical diagnostics, pharmaceuticals, and research laboratories. The market benefits from innovations in microfluidic technology, which enhance the efficiency and accuracy of molecular analysis. Key players in this market include Agilent Technologies, Bio-Rad Laboratories, and PerkinElmer, who are driving advancements and meeting the demand for high-performance analytical instruments. Europe’s strong focus on research and development further propels this market forward.

Asia Pacific Capillary Electrophoresis Market Trends

Asia Pacific market is anticipated to witness the fastest growth of 6.11% CAGR over the forecast period. This is due to market due to rising incidence of cancer and infectious diseases in Asia Pacific is likely driving adoption of advanced diagnostic technologies like capillary electrophoresis and increasing industry academia collaborations in countries like India and China and Japan. Factors driving growth include increasing investments in pharmaceutical and biotechnology research, rising demand for personalized therapeutics, and growing number of clinical and research laboratories in the region.

Key Capillary Electrophoresis Company Insights

Some of the key players operating in the market include Bio-Rad Laboratories, Inc., Thermo Fisher Scientific Inc., Agilent Technologies, Inc., Shimadzu Corporation. and others. The market is highly competitive, with a large number of manufacturers accounting for a majority of the share. New source developments, mergers and acquisitions, and collaborations are some of the major strategies adopted by these players to counter the stiff competition.

Recent Developments

• In January 2024, Agilent Technologies announced a new automated parallel capillary electrophoresis ‘ProteoAnalyzer’ system designed to enhance proteomics research and analysis capabilities. The system integrated advanced liquid chromatography with mass spectrometry (LC-MS) technologies, offering improved sensitivity and throughput for protein characterization and identification. This innovation aimed to address the growing demand for high-resolution proteomics solutions in pharmaceutical research, biomarker discovery, and clinical diagnostics.

• In May 2022, QIAGEN expanded its automation capabilities with the introduction of the QIAxcel Connect, a high-performance capillary electrophoresis instrument that offers rapid, precise, and ultra-sensitive analysis for nucleic acid detection. This latest addition to QIAGEN's automation solutions enables high-speed, high-resolution, and high-sensitivity results for a range of applications

• In June 2021, Thermo Fisher Scientific and Advanced Electrophoresis Solutions Ltd (AES) have partnered to integrate essential protein separation techniques with mass spectrometry (MS), aimed at advancing therapeutic protein development through more efficient characterization. This collaboration will utilize Thermo Fisher's expertise in mass spectrometry technology for biopharma and proteomics applications, complemented by AES' advanced whole column imaging detection capillary electrophoresis systems. Together, these technologies the company will enhance protein separation, quantification, and characterization, offering laboratories in biopharmaceuticals, clinical research, food analysis, and academia advanced capabilities. This partnership is expected to provide scientists with deeper insights into protein analysis, particularly through the enhanced results achieved with Imaged Capillary Isoelectric Focusing (iCIEF) techniques.

Capillary Electrophoresis Market Report Scope

Global Capillary Electrophoresis Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global capillary electrophoresis market report based onproduct, mode, application, end-use, and region

• Product Outlook (Revenue, USD Million, 2018 - 2030)

  • Instrument

    • Automatic Capillary Electrophoresis Systems

    • Semi-Automatic Capillary Electrophoresis Systems

  • Consumables

  • Software

• Mode Outlook (Revenue, USD Million, 2018 - 2030)

  • Capillary zone electrophoresis

  • Capillary gel electrophoresis

  • Capillary electrochromatography

• Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Nucleic acid analysis

  • Protein analysis

  • Genomic DNA

  • Plasmid DNA

  • Fragment Analysis

  • RNA/mRNA Analysis

  • Others

• End-use Outlook (Revenue, USD Million, 2018 - 2030)

  • Research Organizations and Institutes

  • Pharmaceutical & Biotechnology Companies

  • Clinical laboratories

• Regional Outlook (Revenue in USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Sweden

    • Denmark

    • Norway

  • Asia Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

    • Thailand

  • Latin America

    • Brazil

    • Argentina

  • Middle East and Africa

    • Saudi Arabia

    • South Africa

    • UAE

    • Kuwait