Global Non-opioid Pain Treatment Market Size & Outlook

The non-opioid pain treatment industry worldwide is expected to reach a projected revenue of US$ 70,309.5 million by 2030. A compound annual growth rate of 7.6% is expected of the worldwide non-opioid pain treatment industry from 2025 to 2030.
Revenue, 2024 (US$M)
$45,321.9
Forecast, 2030 (US$M)
$70,309.5
CAGR, 2025 - 2030
7.6%
Report Coverage
Worldwide

Global non-opioid pain treatment market, 2018-2030 (US$M)

Global non-opioid pain treatment market highlights

  • The global non-opioid pain treatment market generated a revenue of USD 38,640.2 million in 2021 and is expected to reach USD 77,912.7 million by 2030.
  • The market is expected to grow at a CAGR (2022 - 2030) of 8.1% by 2030.
  • In terms of segment, local anesthetics accounted for a revenue of USD 17,409.0 million in 2021.
  • Acetaminophen is the most lucrative drug class segment registering the fastest growth during the forecast period.
  • In terms of region, North America was the largest revenue generating market in 2021.
  • Country-wise, Sweden is expected to register the highest CAGR from 2022 to 2030.

Global data book summary

Market revenue in 2021USD 38,640.2 million
Market revenue in 2030USD 77,912.7 million
Growth rate8.1% (CAGR from 2021 to 2030)
Largest segmentLocal anesthetics
Fastest growing segmentAcetaminophen
Historical data covered2018 - 2020
Base year for estimation2021
Forecast period covered2022 - 2030
Quantitative unitsRevenue in USD million
Market segmentationNSAIDs, Acetaminophen, Local Anesthetics

Other key industry trends

  • In terms of revenue, the North America accounted for 40.2% of the global non-opioid pain treatment market in 2021.
  • By country, the U.S. is projected to lead the global market in terms of revenue in 2030.
  • By country, Sweden is the fastest growing regional market and is projected to reach USD 874.0 million by 2030.

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Non-opioid Pain Treatment Market Scope

Non-opioid pain treatment market segmentation & scope
Selective COX-2 Inhibitors
Non-Selective NSAIDs
Acetaminophen
Local Anesthetics
Others
Pain Type
Chronic Pain
Neuropathic Pain
Inflammatory Conditions
Post-operative Pain
Cancer Pain
Others
Route of Administration
Oral
Topical
Injectable
Others
Distribution Channel
Hospital Pharmacy
Retail Pharmacy
Others

Non-opioid Pain Treatment Market Companies

Name Profile # Employees HQ Website

Global non-opioid pain treatment market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to non-opioid pain treatment market will help companies and investors design strategic landscapes.


Local anesthetics was the largest segment with a revenue share of 45.05% in 2024. Horizon Databook has segmented the Global non-opioid pain treatment market based on nsaids, acetaminophen, local anesthetics covering the revenue growth of each sub-segment from 2018 to 2030.


  • Global Non-opioid Pain Treatment Drug Class Outlook (Revenue, USD Million, 2018-2030)
    • NSAIDs
      • Selective COX-2 Inhibitors
      • Non-Selective NSAIDs
    • Acetaminophen
    • Local Anesthetics
    • Others
  • Global Non-opioid Pain Treatment Pain Type Outlook (Revenue, USD Million, 2018-2030)
    • Chronic Pain
      • Neuropathic Pain
      • Inflammatory Conditions
    • Post-operative Pain
    • Cancer Pain
    • Others
  • Global Non-opioid Pain Treatment Route of Administration Outlook (Revenue, USD Million, 2018-2030)
    • Oral
    • Topical
    • Injectable
    • Others
  • Global Non-opioid Pain Treatment Distribution Channel Outlook (Revenue, USD Million, 2018-2030)
    • Hospital Pharmacy
    • Retail Pharmacy
    • Others

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Horizon Databook provides a detailed overview of global-level data and insights on the Global non-opioid pain treatment market , including forecasts for subscribers. This global databook contains high-level insights into Global non-opioid pain treatment market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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Global non opioid pain treatment market report size, by regions, 2018-2030 (US$M)

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