U.S. Non-alcoholic Steatohepatitis Biomarkers Market Size & Outlook

The non-alcoholic steatohepatitis biomarkers market in the United States is expected to reach a projected revenue of US$ 2,600.2 million by 2030. A compound annual growth rate of 23.2% is expected of the United States non-alcoholic steatohepatitis biomarkers market from 2025 to 2030.
Revenue, 2024 (US$M)
$730.3
Forecast, 2030 (US$M)
$2,600.2
CAGR, 2025 - 2030
23.2%
Report Coverage
U.S.

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U.S. non-alcoholic steatohepatitis biomarkers market, 2018-2030 (US$M)

U.S. non-alcoholic steatohepatitis biomarkers market, 2018-2030 (US$M)

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U.S. non-alcoholic steatohepatitis biomarkers market highlights

  • The U.S. non-alcoholic steatohepatitis biomarkers market generated a revenue of USD 730.3 million in 2024 and is expected to reach USD 2,600.2 million by 2030.
  • The U.S. market is expected to grow at a CAGR of 23.2% from 2025 to 2030.
  • In terms of segment, serum biomarkers was the largest revenue generating type in 2024.
  • Hepatic Fibrosis Biomarkers is the most lucrative type segment registering the fastest growth during the forecast period.

Non-alcoholic steatohepatitis biomarkers market data book summary

Market revenue in 2024USD 730.3 million
Market revenue in 2030USD 2,600.2 million
Growth rate23.2% (CAGR from 2025 to 2030)
Largest segmentSerum biomarkers
Fastest growing segmentHepatic Fibrosis Biomarkers
Historical data2018 - 2023
Base year2024
Forecast period2025 - 2030
Quantitative unitsRevenue in USD million
Market segmentationSerum Biomarkers, Hepatic Fibrosis Biomarkers, Apoptosis Biomarkers, Oxidative Stress Biomarkers
Key market players worldwideGenfit SA, Siemens AG, Quest Diagnostics Inc, AstraZeneca PLC, Meridian Bioscience, Labcorp Holdings Inc, Pfizer Inc, Bristol-Myers Squibb Co

Other key industry trends

  • In terms of revenue, U.S. accounted for 47.8% of the global non-alcoholic steatohepatitis biomarkers market in 2024.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2030.
  • In North America, U.S. non-alcoholic steatohepatitis biomarkers market is projected to lead the regional market in terms of revenue in 2030.
  • Canada is the fastest growing regional market in North America and is projected to reach USD 251.0 million by 2030.

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Non-alcoholic Steatohepatitis Biomarkers Market Companies

Name Profile # Employees HQ Website
Prometheus Laboratories Inc. View profile 251-500 San Diego, California, United States, North America https://www.prometheuslabs.com/
Exalenz Bioscience View profile 11-50 Union, New Jersey, United States, North America http://www.exalenz.com/
Genfit SA View profile 159 Parc Eurasante, 885, Avenue Eugene Avinee, Loos, France, 59120 https://www.genfit.com
Meridian Bioscience View profile 501-1000 Cincinnati, Ohio, United States, North America http://meridianbioscience.com
AstraZeneca PLC View profile 89900 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, United Kingdom, CB2 0AA https://www.astrazeneca.com
Labcorp Holdings Inc View profile 67000 358 South Main Street, Burlington, NC, United States, 27215 https://www.labcorp.com
Bristol-Myers Squibb Co View profile 34100 Route 206 and Province Line Road, Princeton, New Jersey, NJ, United States, 08543 https://www.bms.com
Quest Diagnostics Inc View profile 48000 500 Plaza Drive, Secaucus, NJ, United States, 07094 https://www.questdiagnostics.com
Siemens AG View profile 321000 Werner-von-Siemens-Strabe 1, Munich, BY, Germany, 80333 https://www.siemens.com
Pfizer Inc View profile 88000 66 Hudson Boulevard East, New York, NY, United States, 10001-2192 https://www.pfizer.com

U.S. non-alcoholic steatohepatitis biomarkers market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to non-alcoholic steatohepatitis biomarkers market will help companies and investors design strategic landscapes.


Serum biomarkers was the largest segment with a revenue share of 40.48% in 2024. Horizon Databook has segmented the U.S. non-alcoholic steatohepatitis biomarkers market based on serum biomarkers, hepatic fibrosis biomarkers, apoptosis biomarkers, oxidative stress biomarkers covering the revenue growth of each sub-segment from 2018 to 2030.


A chronic, progressive condition known as NASH causes fatty liver and liver cell damage before progressing to cirrhosis, fibrosis, and Hepatocellular Cancer (HCC). The diagnosis requires a liver biopsy, however, owing to the expense and invasiveness of the procedure, NASH is still underdiagnosed.

To assess liver health, several companies have developed blood- and imaging-based biomarkers, however, neither of these technologies has been systematically evaluated nor validated against the existing gold standard of liver biopsy.

NIMBLE assessed the existing NASH biomarkers to determine those with enough encouraging data to support further validation. These potential biomarkers will be thoroughly investigated by NIMBLE to gauge their effectiveness in comparison with the gold standard and determine whether they are suitable for widespread use in clinical trials, possibly in place of liver biopsy.

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  • Our clientele includes a mix of non-alcoholic steatohepatitis biomarkers market companies, investment firms, advisory firms & academic institutions.
  • 30% of our revenue is generated working with investment firms and helping them identify viable opportunity areas.
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Horizon Databook provides a detailed overview of country-level data and insights on the U.S. non-alcoholic steatohepatitis biomarkers market , including forecasts for subscribers. This country databook contains high-level insights into U.S. non-alcoholic steatohepatitis biomarkers market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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U.S. non-alcoholic steatohepatitis biomarkers market size, by end use, 2018-2030 (US$M)

U.S. Non-alcoholic Steatohepatitis Biomarkers Market Outlook Share, 2024 & 2030 (US$M)

U.S. non-alcoholic steatohepatitis biomarkers market size, by end use, 2018-2030 (US$M)

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