RNA Therapy Clinical Trials Market To Reach $3.5 Billion By 2030

RNA Therapy Clinical Trials Market Growth & Trends

The global RNA therapy clinical trials market size is expected to reach USD 3.5 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to grow at a CAGR of 3.84% from 2023 to 2030. The growth of the market in emerging countries is due to escalating biotechnology and pharmaceutical companies, the increasing burden of infectious and rare diseases, the growing success rate of RNA-based covid-19 vaccines, regulatory approval, and demand for personalized medicines drive the market growth.

Besides, RNA therapy acts as a promising therapeutic approach for the treatment or prevention of diseases leading to a rise in several RNA clinical trials. Additionally, long-term research activities on various types of RNAs, and the ability of RNA to treat various human diseases and disorders have led to strong demand for the market. Also, the potential benefit of RNA therapy wherein RNA itself serves as either a drug or a target provides acts as an innovative approach for developing new drugs for rare or difficult-to-treat diseases.

Globally, infectious diseases and rare diseases remain the leading cause of death, which has gained the increased attention of biotechnology and pharmaceutical companies to develop new drugs. This led to the rise in the innovation of RNA-based therapy creating immense requirements for RNA therapy clinical trials. Additionally, rare diseases remain the top targeted therapeutic area by RNA therapies.

Furthermore, according to the US Food & Drug Administration, in December 2022, over 7,000 rare diseases affected more than 30 million people in the U.S. whereas according to European Commission as of February 2023, up to 36 million European population live with a rare disease. There are 6000+ distinct rare diseases in the EU. Likewise, the increasing understanding of RNA functions and their roles in disease prevention has promoted various RNAs application.

The COVID-19 pandemic has greatly impacted the growth of the RNA therapy clinical trials market. The sudden focus of pharmaceutical and biotechnology companies on the development of the vaccine, research, and development activities had certainly disrupted the RNA clinical trials across the globe. However, the increasing interest of researchers to develop an RNA-based COVID-19 vaccine has supported the market with positive growth. Additionally, it has also sparked an interest in RNA use against other infectious diseases and oncology indications. These factors drive the growth of the market.

Furthermore, the key participants engage in strategies such as partnerships, agreements, collaborations, and launches, to expand their global footprints and product portfolio. For instance, in March 2021, IQVIA Company announced the collaboration with Janssen Research & Development, LLC for Phase 3 COVID-19 vaccine clinical trials. The studies will support both remote and on-site studies through a mix of virtual oversight, telehealth technologies, and digital patient engagement strategies.

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RNA Therapy Clinical Trail Market Report Highlights

• The messenger RNA segment held the largest revenue share of 35.7% in 2022 owing to increased researchers' study in gene expression, technology advancement has contributed to the segment growth

• The Phase II segment dominated the RNA therapy clinical trials market with a revenue share of 41.3% in 2022. The effectiveness of RNA therapy and the safety of RNA clinical trials will drive segment growth

• In 2022, the rare diseases segment dominated the market and accounted for a revenue share of 21.8%. The key factors contributing to the growth include the growing burden of various types of rare diseases. Also, R&D expenditures made by market players drive the market growth

• North America held the largest revenue share of 36.6% in 2022. The presence of well-established market players, the increasing burden of rare diseases, growing research activities on RNA, rising number of clinical trials drive the regional growth

• Additionally, constant innovation and an emerging number of clinical studies and trials drive the market growth in the region. For instance, in December 2022, Moderna & Merck mentioned the phase 2b KEYNOTE-942/mRNA-4157-P201 trial of mRNA-4157/V940 a personalized mRNA cancer vaccine with KEYTRUDA combination. It is an mRNA cancer vaccine for melanoma stage III/IV patient treatment 

• Key players dominating the market include IQVIA; Laboratory Corporation of America Holdings; ICON Plc; Charles River Laboratories International, Inc.; PPD Inc.; Syneos Health; Medpace Holdings, Inc.; Novotech; PAREXEL International Corp.; and Veristat, LLC

RNA Therapy Clinical Trials Market Segmentation

Grand View Research has segmented the global RNA therapy clinical trials market based on modality, clinical trials phase, therapeutic areas, and region:

RNA Therapy Clinical Trials Modality Outlook (Revenue, USD Million, 2018 - 2030)

• RNA interference

• Antisense therapy

• Messenger RNA

• Oligonucleotide, non-antisense, non-RNAi

RNA Therapy Clinical Trials Phase Outlook (Revenue, USD Million, 2018 - 2030)

• Phase I

• Phase II

• Phase III

• Phase IV

RNA Therapy Clinical Trials Therapeutic Areas Outlook (Revenue, USD Million, 2018 - 2030)

• Rare diseases

• Anti-infective

• Anticancer

• Neurological

• Alimentary/ Metabolic

• Musculoskeletal

• Cardiovascular respiratory

• Sensory

• Others

RNA Therapy Clinical Trials Regional Outlook (Revenue, USD Million, 2018 - 2030)

• North America

  • U.S.

  • Canada

• Europe

  • UK

  • Germany

  • France

  • Italy

  • Spain

  • Sweden

  • Norway

  • Denmark

• Asia Pacific

  • Japan

  • China

  • India

  • South Korea

  • Australia

  • Thailand

• Latin America

  • Brazil

  • Mexico

  • Argentina

• Middle East & Africa

  • South Africa

  • Saudi Arabia

  • UAE

  • Kuwait

List of Key Players in the RNA Therapy Clinical Trials Market

• IQVIA

• ICON Plc

• Laboratory Corporation of America Holdings

• Charles River Laboratories International, Inc.

• PAREXEL International Corp.

• Syneos Health

• Medpace Holdings, Inc.

• PPD Inc.

• Novotech

• Veristat, LLC.