The global microbial fermentation technology market size is expected to reach USD 49.39 billion by 2030, registering a CAGR of 5.8% according to a new report by Grand View Research, Inc. Since fermentation is observed to be of utmost importance in the manufacturing of biopharmaceuticals, there is also a growing demand for microbial fermentation technology in biopharmaceutical manufacturing. This has led to increasing collaborations and developments in this market space.
For instance, in September 2021, BIOVECTRA and ABEC collaboratively announced that the latter company would provide CSR single-use microbial fermentation solutions to expand BIOVECTRA’s manufacturing capabilities. The newly installed solutions are expected to provide a faster turnaround time with high-growth microbial fermentation on large scale. Moreover, in September 2022, Cargill and Genomatica along with Cyclone Engineers are working on a project to scale up the bioreactor fermentation processing. This project is a part of the National Biotechnology and Biomanufacturing Initiative with a grant of USD 2.5 million.
Furthermore, technological advances in microbial fermentation platforms are also expected to supplement the market growth. For instance, several metabolic engineering approaches have been developed by researchers to enhance the performance of microbial cell factories used for the production of complex biologics or small molecules. Such continuous developments in this market space are likely to increase the adoption of this technology in biomanufacturing.
Additionally, various medications and vaccines, such as hormones, antibody fragments, and pneumococcal vaccines, are bio-manufactured using microbial fermentation techniques. Bacterial cells are often resistant to shear damage, enabling the use of high-shear radial impeller systems and high agitation rates. This gives the fermentors a high mass transfer potential, allowing them to accommodate fast metabolizing, high-cell density microbial cell cultivations and increasing the quantity of product that the bioprocesses can produce. Thus, with the increasing adoption of SUB fermentors for bacterial fermentation, the market is likely to witness significant growth in the coming years.
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Based on application, the antibiotics segment captured the highest market revenue share in 2021. Increasing research activities due to the rise of antibiotic-resistant microbes have positively impacted market growth
Owing to the faster and more stable growth pattern of microorganisms, the use of fermentation in small molecule synthesis is expected to witness lucrative growth throughout the forecast period
By end-users, CMOs and CDMOs accounted for a significant share in 2021. The capacity expansion by several CMOs and the growing trend of outsourcing is expected to propel the segment revenue generation
Asia Pacific dominated the market in 2021 owing to the high number of operating CMOs and the growing biopharmaceutical industry in countries such as India, Japan, and China
North America is anticipated to witness the fastest growth throughout the forecast period owing to the presence of a well-established biopharmaceutical industry coupled with a high number of fermentation solution providers
Continuous efforts by key players to improve their product offerings are also contributing to North America’s regional market growth
Grand View Research has segmented the global microbial fermentation technology market report based on application, end-user, and region:
Microbial Fermentation Technology Application Outlook (Revenue, USD Million, 2018 - 2030)
Antibiotics
Probiotics Supplements
Monoclonal Antibodies
Recombinant Proteins
Biosimilars
Vaccines
Enzymes
Small Molecules
Others
Microbial Fermentation Technology End-user Outlook (Revenue, USD Million, 2018 - 2030)
Bio-Pharmaceutical Companies
Contract Research Organizations (CROs)
CMOs & CDMOs
Academic & Research Institutes
Microbial Fermentation Technology Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
Canada
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
South Korea
Australia
Thailand
Latin America
Brazil
Mexico
Argentina
Middle East & Africa
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in Microbial Fermentation Technology Market
Biocon Ltd.
BioVectra Inc.
Danone UK
F. Hoffmann-La Roche AG
Koninklijke DSM NV
Lonza
Novozymes A/S
TerraVia Holdings, Inc.
BIOZEEN
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