U.S. Viscosupplementation Market Size & Outlook, 2025-2033

The viscosupplementation market in the United States is expected to reach a projected revenue of US$ 2,973.3 million by 2033. A compound annual growth rate of 5.4% is expected of the United States viscosupplementation market from 2025 to 2033.
Revenue, 2024 (US$M)
$1,794.7
Forecast, 2033 (US$M)
$2,973.3
CAGR, 2025 - 2033
5.4%
Report Coverage
U.S.

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U.S. viscosupplementation market, 2021-2033 (US$M)

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U.S. viscosupplementation market highlights

  • The U.S. viscosupplementation market generated a revenue of USD 1,794.7 million in 2024 and is expected to reach USD 2,973.3 million by 2033.
  • The U.S. market is expected to grow at a CAGR of 5.4% from 2025 to 2033.
  • In terms of segment, single injection was the largest revenue generating product in 2024.
  • Single Injection is the most lucrative product segment registering the fastest growth during the forecast period.


Viscosupplementation market data book summary

Market revenue in 2024USD 1,794.7 million
Market revenue in 2033USD 2,973.3 million
Growth rate5.4% (CAGR from 2025 to 2033)
Largest segmentSingle injection
Fastest growing segmentSingle Injection
Historical data2021 - 2023
Base year2024
Forecast period2025 - 2033
Quantitative unitsRevenue in USD million
Market segmentationSingle Injection, Three Injection, Five Injection
Key market players worldwideDePuy Synthes, Sanofi SA, Smith & Nephew PLC, Anika Therapeutics Inc, Zimmer Biomet Holdings Inc, Ferring, Lifecore Biomedical Inc, LG Chem, Roche Holding AG


Other key industry trends

  • In terms of revenue, U.S. accounted for 33.9% of the global viscosupplementation market in 2024.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2033.
  • In North America, U.S. viscosupplementation market is projected to lead the regional market in terms of revenue in 2033.
  • Mexico is the fastest growing regional market in North America and is projected to reach USD 137.4 million by 2033.

Single injection was the largest segment with a revenue share of 47.89% in 2024. Horizon Databook has segmented the U.S. viscosupplementation market based on single injection, three injection, five injection covering the revenue growth of each sub-segment from 2021 to 2033.


According to CDC, in 2013–2015, 54 million people in the U.S. were reported to be diagnosed with some form of arthritis. The condition has limited the activities of around 24 million adults and is responsible for severe joint pain in about 15 million adults.

The most common form of arthritis is osteoarthritis followed by rheumatoid arthritis, gout, and fibromyalgia. The rapid rise in geriatric population has led to increase in incidence of osteoarthritis, thus propelling demand for joint-injectable products.

According to Population Reference Bureau, the population of Americans aged 65 or older is projected to increase by twofold from 46 million in 2016 to 98 million by 2060. Multiple-injection products have existed in the market for a long time and, hence, are highly preferred.

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Viscosupplementation Market Companies

Name Profile # Employees HQ Website
Lifecore Biomedical Inc View profile 459 3515 Lyman Boulevard, Chaska, MN, United States, 55318 https://www.lifecore.com
Ferring View profile 5001-10000 Saint-prex, Vaud, Switzerland, Europe https://www.ferring.com
Anika Therapeutics Inc View profile 357 32 Wiggins Avenue, Bedford, MA, United States, 01730 https://www.anika.com
LG Chem View profile 10001+ Seoul, Seoul-t'ukpyolsi, South Korea, Asia https://www.lgchem.com
Smith & Nephew PLC View profile 18452 Hatters Lane, Building 5, Croxley Park, Watford, Hertfordshire, United Kingdom, WD18 8YE https://www.smith-nephew.com
DePuy Synthes View profile 5001-10000 Raynham, Massachusetts, United States, North America https://depuysynthes.com
Zimmer Biomet Holdings Inc View profile 18000 345 East Main Street, Warsaw, IN, United States, 46580 https://www.zimmerbiomet.com
Roche Holding AG View profile 103605 Grenzacherstrasse 124, Basel, Switzerland, 4070 https://www.roche.com
Sanofi SA View profile 87994 46, avenue de la Grande Armée, Paris, France, 75017 https://www.sanofi.com

U.S. viscosupplementation market size, by product, 2021-2033 (US$M)

U.S. Viscosupplementation Market Outlook Share, 2024 & 2033 (US$M)

U.S. viscosupplementation market size, by product, 2021-2033 (US$M)

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