U.S. Upstream Bioprocessing Market Size & Outlook

The upstream bioprocessing market in the United States is expected to reach a projected revenue of US$ 17,586.1 million by 2030. A compound annual growth rate of 12.4% is expected of the United States upstream bioprocessing market from 2024 to 2030.
Revenue, 2023 (US$M)
$8,000.8
Forecast, 2030 (US$M)
$17,586.1
CAGR, 2024 - 2030
12.4%
Report Coverage
U.S.

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U.S. upstream bioprocessing market, 2018-2030 (US$M)

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U.S. upstream bioprocessing market highlights

  • The U.S. upstream bioprocessing market generated a revenue of USD 8,000.8 million in 2023 and is expected to reach USD 17,586.1 million by 2030.
  • The U.S. market is expected to grow at a CAGR of 12.4% from 2024 to 2030.
  • In terms of segment, bioreactors/fermenters was the largest revenue generating product in 2023.
  • Cell Culture Products is the most lucrative product segment registering the fastest growth during the forecast period.


Upstream bioprocessing market data book summary

Market revenue in 2023USD 8,000.8 million
Market revenue in 2030USD 17,586.1 million
Growth rate12.4% (CAGR from 2024 to 2030)
Largest segmentBioreactors/fermenters
Fastest growing segmentCell Culture Products
Historical data2018 - 2022
Base year2023
Forecast period2024 - 2030
Quantitative unitsRevenue in USD million
Market segmentationBioreactors/Fermenters, Cell Culture Products, Filters, Bioreactors Accessories, Bags & Containers
Key market players worldwideThermo Fisher Scientific Inc, Merck KGaA, Corning Inc, Sartorius AG, Eppendorf, Danaher Corp, Boehringer Ingelheim, Getinge AB Class B, Lonza Group Ltd, Avantor Inc, Repligen Corp, Entegris Inc, PBS Biotech, Meissner, Kuhner Shaker


Other key industry trends

  • In terms of revenue, U.S. accounted for 33.2% of the global upstream bioprocessing market in 2023.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2030.
  • In North America, U.S. upstream bioprocessing market is projected to lead the regional market in terms of revenue in 2030.
  • Canada is the fastest growing regional market in North America and is projected to reach USD 1,887.2 million by 2030.

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Upstream Bioprocessing Market Companies

Name Profile # Employees HQ Website
Kuhner Shaker View profile 11-50 Birsfelden, Basel-Landschaft, Switzerland, Europe https://kuhner.com
PBS Biotech View profile 51-100 Camarillo, California, United States, North America http://www.pbsbiotech.com
Entegris Inc View profile 8000 129 Concord Road, Billerica, MA, United States, 01821 https://www.entegris.com
Meissner View profile 51-100 Camarillo, California, United States, North America https://www.meissner.com/
Repligen Corp View profile 1783 41 Seyon Street, Building 1, Suite 100, Waltham, MA, United States, 02453 https://www.repligen.com
Eppendorf View profile 1001-5000 Hamburg, Hamburg, Germany, Europe https://dasgip.de
Corning Inc View profile 49800 One Riverfront Plaza, Corning, NY, United States, 14831 https://www.corning.com
Boehringer Ingelheim View profile 10001+ Ingelheim Am Rhein, Rheinland-Pfalz, Germany, Europe https://www.boehringer-ingelheim.com/
Getinge AB Class B View profile 11862 Lindholmspiren 7A, P.O. Box 8861, Gothenburg, Sweden, SE-417 56 https://www.getinge.com
Avantor Inc View profile 14500 100 Matsonford Road, Suite 200, Building One, Radnor Corporate Center, Radnor, PA, United States, 19087 https://www.avantorsciences.com
Sartorius AG View profile 14338 Otto-Brenner-Strasse 20, Gottingen, NI, Germany, 37079 https://www.sartorius.com
Danaher Corp View profile 63000 2200 Pennsylvania Avenue, N.W., Suite 800W, Washington, DC, United States, 20037-1701 https://www.danaher.com
Thermo Fisher Scientific Inc View profile 122000 168 Third Avenue, Waltham, MA, United States, 02451 https://www.thermofisher.com
Lonza Group Ltd View profile 18000 Muenchensteinerstrasse 38, Basel, Switzerland, CH-4002 https://www.lonza.com
Merck KGaA View profile 62345 Frankfurter Strasse 250, Darmstadt, HE, Germany, 64293 https://www.emdgroup.com

U.S. upstream bioprocessing market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to upstream bioprocessing market will help companies and investors design strategic landscapes.


Bioreactors/fermenters was the largest segment with a revenue share of 34.08% in 2023. Horizon Databook has segmented the U.S. upstream bioprocessing market based on bioreactors/fermenters, cell culture products, filters, bioreactors accessories, bags & containers covering the revenue growth of each sub-segment from 2018 to 2030.


Key companies such as GE Healthcare, Danaher Life Sciences, and Avantor, Inc. that offer a wide product portfolio to support upstream workflows in bioproduction have contributed to market growth in the U.S. These key companies are engaged in several business initiatives to advance in bioprocessing and strengthen their market position.

These bioreactors are expected to simplify single-use upstream bioprocessing procedures. Furthermore, in September 2023, Waters launched new solutions to simplify the cell culture media and biological drug product analysis. Over traditional methods, the solutions optimize the development of upstream bioprocess approximately by six weeks. 

Furthermore, the ongoing national conferences that provide insights into various innovations in upstream bioprocessing are driving product uptake in the country. Moreover, in August 2023, Cambridge Innovation Institute (CII) held its 16th Bioprocessing Summit. It emphasized existing methods of improving bioprocessing, the bioprocessing future, and the potential transformation in the coming years.

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Target buyers of U.S. upstream bioprocessing market databook

  • Our clientele includes a mix of upstream bioprocessing market companies, investment firms, advisory firms & academic institutions.
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Horizon Databook provides a detailed overview of country-level data and insights on the U.S. upstream bioprocessing market , including forecasts for subscribers. This country databook contains high-level insights into U.S. upstream bioprocessing market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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U.S. upstream bioprocessing market size, by product, 2018-2030 (US$M)

U.S. Upstream Bioprocessing Market Outlook Share, 2023 & 2030 (US$M)

U.S. upstream bioprocessing market size, by product, 2018-2030 (US$M)

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