North America Large Molecule Drug Substance Cdmo Market Size & Outlook

The large molecule drug substance cdmo market in North America is expected to reach a projected revenue of US$ 26,946.9 million by 2033. A compound annual growth rate of 7.1% is expected of North America large molecule drug substance cdmo market from 2025 to 2033.
Revenue, 2024 (US$M)
$14,577.8
Forecast, 2033 (US$M)
$26,946.9
CAGR, 2025 - 2033
7.1%
Report Coverage
North America

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North America large molecule drug substance cdmo market, 2021-2033 (US$M)

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North America large molecule drug substance cdmo market highlights

  • The North America large molecule drug substance cdmo market generated a revenue of USD 14,577.8 million in 2024.
  • The market is expected to grow at a CAGR of 7.1% from 2025 to 2033.
  • In terms of segment, contract manufacturing was the largest revenue generating service in 2024.
  • Contract Development is the most lucrative service segment registering the fastest growth during the forecast period.
  • Country-wise, Mexico is expected to register the highest CAGR from 2025 to 2033.


North America data book summary

Market revenue in 2024USD 14,577.8 million
Market revenue in 2033USD 26,946.9 million
Growth rate7.1% (CAGR from 2025 to 2033)
Largest segmentContract manufacturing
Fastest growing segmentContract Development
Historical data covered2021 - 2023
Base year for estimation2024
Forecast period covered2025 - 2033
Quantitative unitsRevenue in USD million
Market segmentationContract Manufacturing, Contract Development
Key market players worldwideEurofins Scientific SE, WuXi Biologics (Cayman) Inc, Catalent Inc, AGC Inc, Siegfried Holding AG, Boehringer Ingelheim, FUJIFILM Holdings Corp, Samsung BioLogics, Rentschler Biopharma SE, Recipharm


Other key industry trends

  • In terms of revenue, North America region accounted for 28.0% of the global large molecule drug substance cdmo market in 2024.
  • Globally, Asia Pacific is projected to lead the regional market in terms of revenue in 2033.
  • Asia Pacific is the fastest growing regional market and is projected to reach USD 40,850.4 million by 2033.

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Large Molecule Drug Substance CDMO Market Companies

Name Profile # Employees HQ Website
Samsung BioLogics View profile 1001-5000 Incheon, Inch'on-jikhalsi, South Korea, Asia https://www.samsungbiologics.com/
Recipharm View profile 1001-5000 Jordbro, Stockholms Lan, Sweden, Europe http://www.recipharm.com
Rentschler Biopharma SE View profile 501-1000 Laupheim, Baden-Wurttemberg, Germany, Europe https://www.rentschler-biopharma.com
Siegfried Holding AG View profile 4180 Untere Bruehlstrasse 4, Zofingen, Switzerland, CH-4800 https://www.siegfried.ch
Catalent Inc View profile 17219 14 Schoolhouse Road, Somerset, NJ, United States, 08873 https://www.catalent.com
WuXi Biologics (Cayman) Inc View profile 12740 No. 108, Meiliang Road, Mashan Binhu District, Wuxi, China, People's Republic of, 214092 https://www.wuxibiologics.com
AGC Inc View profile 61671 1-5-1, Marunouchi, Chiyoda-ku, Tokyo, Japan, 100-8405 https://www.agc.com
Boehringer Ingelheim View profile 10001+ Ingelheim Am Rhein, Rheinland-Pfalz, Germany, Europe https://www.boehringer-ingelheim.com/
Eurofins Scientific SE View profile 61798 23 Val Fleuri, Luxembourg, Luxembourg, L-1526 https://www.eurofins.com
FUJIFILM Holdings Corp View profile 83784 7-3, Akasaka 9-chome, Minato-ku, Tokyo, Japan, 107-0052 http://www.fujifilmholdings.com

North America large molecule drug substance cdmo market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to large molecule drug substance cdmo market will help companies and investors design strategic landscapes.


Contract manufacturing was the largest segment with a revenue share of 73.1% in 2024. Horizon Databook has segmented the North America large molecule drug substance cdmo market based on contract manufacturing, contract development covering the revenue growth of each sub-segment from 2021 to 2033.


North America is one of the major contributors of large molecule drug substance CDMO market. This region is home to a large number of biopharmaceutical companies that outsource part of their manufacturing activities to CMOs and CDMOs, thereby contributing to market growth.

Increase in cost of developing large molecules is a major challenge, which has encouraged biopharmaceutical companies in North America to outsource few processes to CDMOs with expertise in the domain.

Moreover, global biopharmaceutical companies prefer CMOs based in North America to easily access the market. It is characterized by presence of several established biopharmaceuticals, pharmaceutical, and contract research organizations.

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Horizon Databook provides a detailed overview of continent-level data and insights on the North America large molecule drug substance cdmo market , including forecasts for subscribers. This continent databook contains high-level insights into North America large molecule drug substance cdmo market from 2021 to 2033, including revenue numbers, major trends, and company profiles.

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North America large molecule drug substance cdmo market size, by country, 2021-2033 (US$M)

North America Large Molecule Drug Substance CDMO Market Outlook Share, 2024 & 2033 (US$M)

North America large molecule drug substance cdmo market size, by country, 2021-2033 (US$M)

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