North America Hormone Replacement Therapy Market Size & Outlook

The hormone replacement therapy market in North America is expected to reach a projected revenue of US$ 17,315.5 million by 2033. A compound annual growth rate of 7.5% is expected of North America hormone replacement therapy market from 2025 to 2033.
Revenue, 2024 (US$M)
$9,145.6
Forecast, 2033 (US$M)
$17,315.5
CAGR, 2025 - 2033
7.5%
Report Coverage
North America

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North America hormone replacement therapy market, 2021-2033 (US$M)

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North America hormone replacement therapy market highlights

  • The North America hormone replacement therapy market generated a revenue of USD 9,145.6 million in 2024.
  • The market is expected to grow at a CAGR of 7.5% from 2025 to 2033.
  • In terms of segment, estrogen and progesterone replacement therapy was the largest revenue generating product in 2024.
  • Parathyroid Hormone replacement is the most lucrative product segment registering the fastest growth during the forecast period.
  • Country-wise, Canada is expected to register the highest CAGR from 2025 to 2033.

North America data book summary

Market revenue in 2024USD 9,145.6 million
Market revenue in 2033USD 17,315.5 million
Growth rate7.5% (CAGR from 2025 to 2033)
Largest segmentEstrogen and progesterone replacement therapy
Fastest growing segmentParathyroid Hormone replacement
Historical data covered2021 - 2023
Base year for estimation2024
Forecast period covered2025 - 2033
Quantitative unitsRevenue in USD million
Market segmentationEstrogen and Progesterone Replacement Therapy, HGH replacement therapy, Thryoid hormone replacement therapy, Testosterone Replacement Therapy, Parathyroid Hormone replacement
Key market players worldwideEli Lilly and Co, Bayer AG, Hisamitsu Pharmaceutical Co Inc, Pfizer Inc, Merck & Co Inc, Viatris Inc, Novo Nordisk A/S ADR, AbbVie Inc, Roche Holding AG ADR, Ascend Wellness Holdings Inc

Other key industry trends

  • In terms of revenue, North America region accounted for 38.8% of the global hormone replacement therapy market in 2024.
  • Globally, North America is projected to lead the regional market in terms of revenue in 2033.
  • Asia Pacific is the fastest growing regional market and is projected to reach USD 10,887.9 million by 2033.

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Hormone Replacement Therapy Market Companies

Name Profile # Employees HQ Website
Ascend Wellness Holdings Inc View profile 1500 1411 Broadway, 16th Floor, New York, NY, United States, 10018 https://www.awholdings.com
Hisamitsu Pharmaceutical Co Inc View profile 3682 408 Tashiro Daikan-machi, Tosu, Saga, Japan, 841-0017 http://www.hisamitsu.co.jp
Viatris Inc View profile 38000 1000 Mylan Boulevard, Canonsburg, PA, United States, 15317 https://www.viatris.com
Novo Nordisk A/S ADR View profile 66015 Novo Alle 1, Bagsvaerd, Denmark, 2880 https://www.novonordisk.com
Eli Lilly and Co View profile 43000 Lilly Corporate Center, Indianapolis, IN, United States, 46285 https://www.lilly.com
Bayer AG View profile 99723 Kaiser-Wilhelm-Allee 1, Leverkusen, NW, Germany, 51368 https://www.bayer.com
Merck & Co Inc View profile 72000 126 East Lincoln Avenue, Rahway, NJ, United States, 07065 https://www.merck.com
Pfizer Inc View profile 88000 66 Hudson Boulevard East, New York, NY, United States, 10001-2192 https://www.pfizer.com
AbbVie Inc View profile 50000 1 North Waukegan Road, North Chicago, IL, United States, 60064-6400 http://www.abbvieinvestor.com
Roche Holding AG ADR View profile 103605 Grenzacherstrasse 124, Basel, Switzerland, 4070 https://www.roche.com

North America hormone replacement therapy market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to hormone replacement therapy market will help companies and investors design strategic landscapes.


Estrogen and progesterone replacement therapy was the largest segment with a revenue share of 59.88% in 2024. Horizon Databook has segmented the North America hormone replacement therapy market based on estrogen and progesterone replacement therapy, hgh replacement therapy, thryoid hormone replacement therapy, testosterone replacement therapy, parathyroid hormone replacement covering the revenue growth of each sub-segment from 2021 to 2033.


North America accounted for the largest share in 2021. Technological advancements, major product launches, collaborative agreements between manufacturers, easy accessibility of quality medical facilities, and favorable reimbursement policies are among factors responsible for the largest market share held by the region.

The healthcare system in North America relies mostly on the government to provide healthcare services and health insurance. The active involvement of the government to provide quality and ease of such services make the U.S. and Canada prominent markets. The prevalence of hormonal disorders is moderately high in this region.

Growth Hormone Deficiency (GHD) in the region ranges from one in 4,000 to one in 10,000 people. In adults, the incidence of GHD is estimated to be around one in 100,000, whereas, in children, the incidence of GHD is approximately two in 100,000 annually. About 15% to 20% of pediatric cases show disease transition into adulthood.

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Target buyers of North America hormone replacement therapy market databook

  • Our clientele includes a mix of hormone replacement therapy market companies, investment firms, advisory firms & academic institutions.
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Horizon Databook provides a detailed overview of continent-level data and insights on the North America hormone replacement therapy market , including forecasts for subscribers. This continent databook contains high-level insights into North America hormone replacement therapy market from 2021 to 2033, including revenue numbers, major trends, and company profiles.

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North America hormone replacement therapy market size, by country, 2021-2033 (US$M)

North America Hormone Replacement Therapy Market Outlook Share, 2024 & 2033 (US$M)

North America hormone replacement therapy market size, by country, 2021-2033 (US$M)

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