U.S. Hereditary Angioedema Therapeutics Market Size & Outlook

The hereditary angioedema therapeutics market in the United States is expected to reach a projected revenue of US$ 2,047.2 million by 2030. A compound annual growth rate of 10.3% is expected of the United States hereditary angioedema therapeutics market from 2024 to 2030.
Revenue, 2023 (US$M)
$1,030.4
Forecast, 2030 (US$M)
$2,047.2
CAGR, 2024 - 2030
10.3%
Report Coverage
U.S.

U.S. hereditary angioedema therapeutics market, 2018-2030 (US$M)

U.S.

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U.S. hereditary angioedema therapeutics market highlights

  • The U.S. hereditary angioedema therapeutics market generated a revenue of USD 1,030.4 million in 2023 and is expected to reach USD 2,047.2 million by 2030.
  • The U.S. market is expected to grow at a CAGR of 10.3% from 2024 to 2030.
  • In terms of segment, kallikrein inhibitor was the largest revenue generating treatment in 2023.
  • Kallikrein inhibitor is the most lucrative treatment segment registering the fastest growth during the forecast period.


Hereditary angioedema therapeutics market data book summary

Market revenue in 2023USD 1,030.4 million
Market revenue in 2030USD 2,047.2 million
Growth rate10.3% (CAGR from 2023 to 2030)
Largest segmentKallikrein inhibitor
Fastest growing segmentKallikrein inhibitor
Historical data2018 - 2022
Base year2023
Forecast period2024 - 2030
Quantitative unitsRevenue in USD million
Market segmentationC1-esterase inhibitor, Bradykinin B2 receptor antagonist, Kallikrein inhibitor, Others Treatment
Key market players worldwideBioCryst Pharmaceuticals Inc, Ionis Pharmaceuticals Inc, CSL Ltd, Adverum Biotechnologies Inc, KalVista Pharmaceuticals Inc, Takeda Pharmaceutical Co Ltd, Pharming Group, Attune Pharmaceuticals


Other key industry trends

  • In terms of revenue, U.S. accounted for 37.1% of the global hereditary angioedema therapeutics market in 2023.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2030.
  • In North America, U.S. hereditary angioedema therapeutics market is projected to lead the regional market in terms of revenue in 2030.
  • Canada is the fastest growing regional market in North America and is projected to reach USD 228.0 million by 2030.

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Hereditary Angioedema Therapeutics Market Companies

Name Profile # Employees HQ Website

U.S. hereditary angioedema therapeutics market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to hereditary angioedema therapeutics market will help companies and investors design strategic landscapes.


Kallikrein inhibitor was the largest segment with a revenue share of 44.72% in 2023. Horizon Databook has segmented the U.S. hereditary angioedema therapeutics market based on c1-esterase inhibitor, bradykinin b2 receptor antagonist, kallikrein inhibitor, others treatment covering the revenue growth of each sub-segment from 2018 to 2030.


High incidence of HAE, growing awareness about the disease, and availability of advanced pharmaceutical technologies are likely to propel the market in the country. Although the prevalence data is unclear, there are an estimated 15,000 to 30,000 emergency admissions for HAE episodes in the U.S. annually, and around 6,000 people are living with the condition.

The presence of private and public organizations focusing on the wellbeing of patients is further propelling the market. For instance, the U.S. Hereditary Angioedema Association is a nonprofit organization focusing on advancing research to benefit people suffering from HAE.

Furthermore, the presence of key market players and the introduction of technologically advanced are driving the country's market. For instance, in January 2021, Glenmark Pharmaceuticals announced the FDA approval of generic version of Firazyr (icatibant injection) for treatment of swelling attacks in HAE patients in the U.S.

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Horizon Databook provides a detailed overview of country-level data and insights on the U.S. hereditary angioedema therapeutics market, including forecasts for subscribers. This country databook contains high-level insights into U.S. hereditary angioedema therapeutics market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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U.S. hereditary angioedema hae therapeutics market size, by treatment, 2018-2030 (US$M)

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