North America Gastroesophageal Reflux Disease Therapeutics Market Size & Outlook

The gastroesophageal reflux disease therapeutics market in North America is expected to reach a projected revenue of US$ 2,109.7 million by 2030. A compound annual growth rate of 1.2% is expected of North America gastroesophageal reflux disease therapeutics market from 2025 to 2030.
Revenue, 2024 (US$M)
$1,959.9
Forecast, 2030 (US$M)
$2,109.7
CAGR, 2025 - 2030
1.2%
Report Coverage
North America

North America gastroesophageal reflux disease therapeutics market, 2018-2030 (US$M)

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North America gastroesophageal reflux disease therapeutics market highlights

  • The North America gastroesophageal reflux disease therapeutics market generated a revenue of USD 1,959.9 million in 2024.
  • The market is expected to grow at a CAGR of 1.2% from 2025 to 2030.
  • In terms of segment, antacids was the largest revenue generating drug type in 2024.
  • H2 Receptor Blockers is the most lucrative drug type segment registering the fastest growth during the forecast period.
  • Country-wise, Mexico is expected to register the highest CAGR from 2025 to 2030.

North America data book summary

Market revenue in 2024USD 1,959.9 million
Market revenue in 2030USD 2,109.7 million
Growth rate1.2% (CAGR from 2025 to 2030)
Largest segmentAntacids
Fastest growing segmentH2 Receptor Blockers
Historical data covered2018 - 2023
Base year for estimation2024
Forecast period covered2025 - 2030
Quantitative unitsRevenue in USD million
Market segmentationAntacids, H2 Receptor Blockers, Proton Pump Inhibitors (PPIs), Pro-kinetic agents
Key market players worldwideAstraZeneca PLC, Eisai Co Ltd, GSK PLC, Takeda Pharmaceutical Co Ltd, Ironwood Pharmaceuticals Inc Class A, Johnson & Johnson, Phathom Pharmaceuticals Inc Ordinary shares

Other key industry trends

  • In terms of revenue, North America region accounted for 38.4% of the global gastroesophageal reflux disease therapeutics market in 2024.
  • Globally, North America is projected to lead the regional market in terms of revenue in 2030.
  • Asia Pacific is the fastest growing regional market and is projected to reach USD 1,556.7 million by 2030.

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Gastroesophageal Reflux Disease Therapeutics Market Companies

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North America gastroesophageal reflux disease therapeutics market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to gastroesophageal reflux disease therapeutics market will help companies and investors design strategic landscapes.


Antacids was the largest segment with a revenue share of 57.47% in 2024. Horizon Databook has segmented the North America gastroesophageal reflux disease therapeutics market based on antacids, h2 receptor blockers, proton pump inhibitors (ppis), pro-kinetic agents covering the revenue growth of each sub-segment from 2018 to 2030.


The rise in incidence of GERD in North America is responsible for increase in demand for acid reducing and neutralizing drugs. In addition, the self-medication trend for management of digestive and gastrointestinal disorders has become popular, owing to convenience, time saved, and cost-effectiveness. 

Based on a study published by National Center for Biotechnology Information (NCBI) in the year 2014, the prevalence GERD in North America ranges between 18% and 28%. Rise in initiatives for creating awareness and educating people is expected to boost the regional market. 

For instance, the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) foundation promotes awareness, education, and research on reflux and GERD.

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Horizon Databook provides a detailed overview of continent-level data and insights on the North America gastroesophageal reflux disease therapeutics market , including forecasts for subscribers. This continent databook contains high-level insights into North America gastroesophageal reflux disease therapeutics market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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North America gastroesophageal reflux disease therapeutics market size, by country, 2018-2030 (US$M)

North America Gastroesophageal Reflux Disease Therapeutics Market Outlook Share, 2024 & 2030 (US$M)

North America gastroesophageal reflux disease therapeutics market size, by country, 2018-2030 (US$M)

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