U.S. Biologics Market Size & Outlook, 2024-2030

The biologics market in the United States is expected to reach a projected revenue of US$ 300,858.9 million by 2030. A compound annual growth rate of 7.7% is expected of the United States biologics market from 2025 to 2030.
Revenue, 2024 (US$M)
$192,408.6
Forecast, 2030 (US$M)
$300,858.9
CAGR, 2025 - 2030
7.7%
Report Coverage
U.S.

U.S. biologics market highlights

  • The U.S. biologics market generated a revenue of USD 192,408.6 million in 2024 and is expected to reach USD 300,858.9 million by 2030.
  • The U.S. market is expected to grow at a CAGR of 7.7% from 2025 to 2030.
  • In terms of segment, monoclonal antibodies (mabs) was the largest revenue generating product in 2024.
  • Antisense & RNAi Therapeutics is the most lucrative product segment registering the fastest growth during the forecast period.

Biologics market data book summary

Market revenue in 2024USD 192,408.6 million
Market revenue in 2030USD 300,858.9 million
Growth rate7.7% (CAGR from 2025 to 2030)
Largest segmentMonoclonal antibodies (mabs)
Fastest growing segmentAntisense & RNAi Therapeutics
Historical data2018 - 2023
Base year2024
Forecast period2025 - 2030
Quantitative unitsRevenue in USD million
Market segmentationMonoclonal antibodies (MABs), Vaccines, Recombinant Proteins, Antisense & RNAi Therapeutics
Key market players worldwideSamsung BioLogics, Amgen Inc, Novo Nordisk A/S ADR, AbbVie Inc, Sanofi SA, Johnson & Johnson, Celltrion Healthcare, Bristol-Myers Squibb Co, Eli Lilly and Co, Roche Holding AG ADR

Other key industry trends

  • In terms of revenue, U.S. accounted for 48.1% of the global biologics market in 2024.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2030.
  • In North America, U.S. biologics market is projected to lead the regional market in terms of revenue in 2030.
  • Canada is the fastest growing regional market in North America and is projected to reach USD 41,805.0 million by 2030.

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Biologics Market Companies

Name Profile # Employees HQ Website

U.S. biologics market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to biologics market will help companies and investors design strategic landscapes.


Monoclonal antibodies (mabs) was the largest segment with a revenue share of 69.01% in 2024. Horizon Databook has segmented the U.S. biologics market based on monoclonal antibodies (mabs), vaccines, recombinant proteins, antisense & rnai therapeutics covering the revenue growth of each sub-segment from 2018 to 2030.


The U.S market for biologics accounted for the significant share in 2017 owing to rising R&D spending for biologic development coupled with the presence of a large number of FDA-approved drugs in the country.

The U.S. is hosting a large number of biologics pipelines in various stages of development. More than 900 biological molecules are under clinical investigation in the country. Steady growth in the number of new biological approvals in the country is anticipated to boost revenue generation for the U.S. market of biologics.

In 2015, 13 new therapeutic biologics were approved. In 2014, 10 top-selling biologics of U.S.-based companies such as Amgen and Biogen accounted for USD 73 billion with respect to revenue generation. Moreover, AbbVie’s HUMIRA is estimated to generate the highest revenue with USD 12.5 billion in sales.

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Horizon Databook provides a detailed overview of country-level data and insights on the U.S. biologics market , including forecasts for subscribers. This country databook contains high-level insights into U.S. biologics market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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U.S. biologics market size, by product, 2018-2030 (US$M)

U.S. Biologics Market Outlook Share, 2024 & 2030 (US$M)

U.S. biologics market size, by product, 2018-2030 (US$M)

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