The global erythropoietin drugs market size is expected to reach USD 7.8 billion expanding at a CAGR of 1.5% from 2023 to 2030, according to a new report by Grand View Research, Inc., The slow growth can be attributed to the patent expiry of multiple biologics, increasing approval and penetration of biosimilars, and declining prices. For instance, PanGen Biotech Inc. is developing Erisa (PDA10). This erythropoietin biosimilar drug is under phase 3 clinical trial to check the safety and efficacy of the drug in patients with anemia.
The U.S. Department of Health and Human Services runs the National Kidney Disease Education Program to raise awareness about chronic kidney disease conditions among patients and physicians. The kidney is the sole source of erythropoietin synthesis in adults. In progressive CKD, the kidney mass decreases, which results in the impairment of erythropoietin production, thereby causing anemia. Thus, the rising awareness about the disease and its available EPO medicines among patients and physicians is anticipated to drive the market.
Increasing demand for cheaper EPO drugs in Asia Pacific, Africa, and the Middle East has triggered the entry of new players in the erythropoietin drugs market. Thus, some of the key players are engaged in the development and commercialization of biosimilars. For instance, Novotech (Australia) Pty Limited has an EPO biosimilar, Efepoetin alfa in phase 3 trials.
Safety concerns with EPO agents have encouraged the development of alternative treatments for anemia. For instance, HIF-PH inhibitors such as roxudustat (AstraZeneca) and daprodustat (GSK) have been approved in Japan, China, and South Korea amongst others. In March 2022, Zydus Lifesciences Ltd. received approval for Oxemia (Desidustat) from the Drug Controller General of India (DCGI). It is an alternative to injectable erythropoietin-stimulating agents. Oxemia is a potential product, a first-of-its-kind oral treatment in India, for anemia associated with chronic kidney diseases, thereby solving unmet needs. The approval of these alternative drugs is expected to negatively impact market growth.
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By type, the biologics segment accounted for the largest share of the market in 2022. This can be attributed to the availability of FDA-approved EPO biologics for the treatment of cancer-induced anemia and CKD patients.
Based on product, the erythropoietin segment dominated the EPO drugs market in 2022 owing to the higher number of approved products and higher prescription rate of erythropoietin.
The renal diseases segment dominated the EPO drugs market in 2022. The high prevalence of CKD and the high prescription rate of EPO drugs are major factors contributing to the dominance of this segment. According to the National Kidney Foundation (NKF), 10% of the total population is affected by chronic kidney disease (CKD) worldwide.
North America dominated the global market in 2022 owing to factors such as late approval and lower penetration of biosimilars in the market
Grand View Research has segmented the global erythropoietin drugs market report based on, type, product, application, and region:
Erythropoietin Drugs Type Outlook (Revenue, USD Million, 2018 - 2030)
Biologics
Biosimilars
Erythropoietin Drugs Product Outlook (Revenue, USD Million, 2018 - 2030)
Erythropoietin
Darbepoetin-alfa
Erythropoietin Drugs Application Outlook (Revenue, USD Million, 2018 - 2030)
Cancer
Renal Diseases
Neurology
Others
Erythropoietin Drugs Regional Outlook (Revenue, USD Million; 2018 - 2030)
North America
U.S.
Canada
Europe
Germany
U.K.
France
Italy
Spain
Denmark
Sweden
Norway
Rest of Europe
Asia Pacific
China
India
Japan
Australia
South Korea
Thailand
Rest of APAC
Latin America
Brazil
Mexico
Argentina
Rest of LATAM
Middle East & Africa
South Africa
Saudi Arabia
UAE
Kuwait
Rest of MEA
List of key players in the Erythropoietin Drugs Market
Johnson & Johnson Services, Inc.
Novartis AG
Teva Pharmaceutical Industries Ltd.
Amgen, Inc.
F. Hoffmann-La Roche Ltd.
LG Chem
Biocon
Intas Pharmaceuticals Ltd.
Sun Pharmaceutical Industries Ltd
Dr. Reddy’s Laboratories Ltd
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