The North America OTC hyaluronic acid market size was valued at USD 6.01 billion in 2023 and is projected to grow at a CAGR of 7.9% from 2024 to 2030. North America over-the-counter (OTC) hyaluronic acid Market growth is fueled by growing consumer awareness of beauty and health benefits as well as the increasing prevalence of chronic illnesses and rising healthcare costs. Hyaluronic acid is used to prevent pollution damage, combat natural aging, and improve skin health, driving demand for this versatile ingredient.
Market growth worldwide is driven by several key factors, including the increasing demand for anti-aging and skincare products. Hyaluronic acid (HA) is widely used in topical skincare products due to its ability to hydrate and plump the skin, reducing the appearance of fine lines and wrinkles. The growing popularity of HA in anti-aging creams, serums, and moisturizers is a major driver of the North America OTC HA market.
The demand for HA products is also fueled by rising consumer awareness of its benefits, including its ability to improve skin hydration, joint health, and wound healing. Moreover, the availability of diverse HA products, such as topical creams, serums, eye drops, and supplements, caters to diverse consumer needs and preferences. The regulatory landscape in North America is also relatively favorable for OTC HA products, with clear guidelines and approvals contributing to the market’s growth.
HA is a versatile ingredient used primarily in beauty and skincare items, offering various benefits. It has also been combined with vitamin C to lighten skin tone. The growing trend of local skincare brands focusing on natural ingredients has seen an increase in financial backing, driven by consumer fascination with these products. The demand for HA is expected to continue to rise as new technologies develop more effective products. The cosmetic industry is attracting customers with advancements in dermal filler procedures and HA-based products, indicating a promising future for business opportunities in this field. Furthermore, raising awareness about anti-aging products is expected to drive up demand for anti-aging cosmetic and esthetic procedures, making HA a key player in this trend.
Dermatology accounted for the largest market revenue share in 2023. Dermatology is sub segmented into two types one is moisturizers and other is anti-wrinkle crème. The proliferation of dermatology clinics in both developed and developing countries is driving the growth of the HA market, with a subsequent increase in the use of dermal fillers expected in the future. Furthermore, the rapid growth of this segment is being fueled by a surge in demand for HA-based fillers for various procedures, as well as a rise in cases of skin concerns such as wrinkles, acne, and scarring.
Orthopedics is expected to register the fastest CAGR of 16.0% during the forecast period. The demand for over-the-counter (OTC) products with HA applicable in orthopedics is increasing globally, driven by the rise of musculoskeletal disorders, sports injuries, and fractures. The growing elderly population and technological advancements in orthopedic devices, such as joint replacements and minimally invasive surgery, are also contributing to the market’s rapid expansion, with developing regions expected to experience significant growth.
Retail accounted for the largest market revenue share of 83.7% in 2023. One of the main factors that is anticipated to drive the market is the easy access to cosmetics and joint supplements in drug stores, departmental stores, and supermarkets. Retail stores offer a vast array of HA serums for individual needs. They provide guidance and assistance to patients on medication usage and possible side effects, leading to a rise in their favor among patients. A lot of patients opt for retail sales channels in the HA market because of its convenience, particularly for prolonged treatment.
Online is expected to register the fastest CAGR of 12.3% during the forecast period. The market is expected to be driven by the rise in internet users in developed economies, particularly in North America, where it is the largest spender on cosmetics and beauty products. This growth is expected to be fueled by the increasing online presence of players, which is expected to increase market share in the future.
North America OTC hyaluronic acid market dominated the global OTC hyaluronic acid market in 2023. The region’s OTC hyaluronic acid market is driven by a strong healthcare sector and growing awareness. Moreover, its adoption of new skincare treatments and technologies are likely to continue fueling the market growth. A large elderly population, susceptible to osteoarthritis, vesicoureteral reflux, and cataracts, and the increasing demand for minimally invasive cosmetic procedures are key factors driving market growth in the region.
The over-the-counter hyaluronic acid market in the U.S. dominated the market in 2023 due to the innovation and the range of products offered, the cosmetic sector in the U.S. is one of the most thriving and mature. In addition, an increase in the cataract and other eye surgeries has led to the increased use of the viscoelastic instruments and eye drops with HA. For instance, based on a survey by the American Academy of Ophthalmology, 2 million cataract surgeries are performed in U.S. every year.
The Mexico over-the-counter hyaluronic acid market is posed for significant growth as the country’s growing middle class and increasing disposable incomes have driven demand for premium skincare and anti-aging products containing HA. The country’s aging population and osteoarthritis prevalence have also fueled uptake of OTC supplements and topical treatments. Mexico’s favorable regulatory environment and diverse product offerings have contributed to the market’s growth in the North American region.
Some key companies in the North America over-the-counter hyaluronic acid market include Shiseido Company; Lindberg Nutrition Products; Nature’s Way; and Now Foods. In a bid to maintain a competitive advantage, significant market participants are prioritizing the expansion of their customer base. To achieve this objective, key players are implementing strategic initiatives, including mergers and acquisitions, as well as collaborative partnerships with other prominent companies.
Earth Science offers a range of plant-based skin, body, and hair care products that prioritize sustainability and wellness, sourced from healthful and eco-friendly ingredients. The company also caters to individual customers’ unique skin care needs by offering products specifically designed for various skin types, with a focus on beauty and facial care.
NeoCell Corporation offers collagen supplements that aim to support youthful vitality, glowing beauty, and overall health. The company provides collagen supplements that are specifically designed to promote health in joints, bones, and muscles. These supplements are made with advanced formulas consisting of top-notch ingredients such as collagen, biotin, and HA.
In April 2024, Shiseido Company discovered CCN2, which was found to have a positive effect on capillaries and increase the levels of key components essential for achieving healthy-looking skin. Moreover, the company conducted research on Serpin b3, a previously identified factor that was found to accelerate skin aging.
Report Attribute |
Details |
Market size value in 2024 |
USD 6.52 billion |
Revenue forecast in 2030 |
USD 10.29 billion |
Growth rate |
CAGR of 7.9% from 2024 to 2030 |
Base year for estimation |
2023 |
Historical data |
2018 - 2022 |
Forecast period |
2024 - 2030 |
Quantitative units |
Revenue in USD million/billion, and CAGR from 2024 to 2030 |
Report coverage |
Revenue forecast, company ranking, competitive landscape, growth factors, and trends |
Segments covered |
Product, sales channel, country |
Regional scope |
North America |
Country scope |
U.S., Canada, Mexico |
Key companies profiled |
Shiseido Company; Lindberg Nutrition Products; Nature’s Way ; Now Foods; NeoCell Corporation; Source Naturals, Inc.; Doctor’s Best; Derma E; Earth Science |
Customization scope |
Free report customization (equivalent up to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope. |
Pricing and purchase options |
Avail customized purchase options to meet your exact research needs. Explore purchase options |
This report forecasts revenue growth at regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the North America OTC hyaluronic acid market report based on product, sales channel, and country.
Product Outlook (Revenue, USD Million, 2018 - 2030)
Dermatology
Moisturizers
Anti-wrinkle Crème
Orthopedics
Sales Channel Outlook (Revenue, USD Million, 2018 - 2030)
Retail
Online
Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
California
Texas
New York
Florida
Illinois
Other States
Canada
Mexico
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